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    Ccdc172 coiled-coil domain containing 172 [ Mus musculus (house mouse) ]

    Gene ID: 75645, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ccdc172provided by MGI
    Official Full Name
    coiled-coil domain containing 172provided by MGI
    Primary source
    MGI:MGI:1922895
    See related
    Ensembl:ENSMUSG00000025090 AllianceGenome:MGI:1922895
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700011F14Rik
    Summary
    Located in cytoplasm. Orthologous to human CCDC172 (coiled-coil domain containing 172). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 3.7) See more
    Orthologs
    human all
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    Genomic context

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    See Ccdc172 in Genome Data Viewer
    Location:
    19 D2; 19 54.35 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (58500416..58546504)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (58511985..58553104)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41876 Neighboring gene predicted gene, 33306 Neighboring gene STARR-seq mESC enhancer starr_46577 Neighboring gene STARR-seq mESC enhancer starr_46578 Neighboring gene STARR-seq mESC enhancer starr_46581 Neighboring gene RIKEN cDNA 1810007D17 gene Neighboring gene pancreatic lipase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and subcellular localization of Tektin2-binding protein 1 (Ccdc 172) in rat spermatozoa. Yamaguchi A, et al. J Histochem Cytochem, 2014 Apr. PMID 24394471, Free PMC Article
    2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Clone Names

    • MGC58650

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in sperm midpiece ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in sperm midpiece ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 172
    Names
    TEKT2-binding protein 2
    UPF0628 protein C10orf96 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001373968.2 → NP_001360897.2  coiled-coil domain-containing protein 172 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC158904
      UniProtKB/Swiss-Prot
      Q810N9, Q9DAG3
      Conserved Domains (1) summary
      TIGR02168
      Location:17 → 203
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    2. NM_001373969.2 → NP_001360898.1  coiled-coil domain-containing protein 172 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC158904
      Consensus CDS
      CCDS38029.1
      UniProtKB/Swiss-Prot
      Q810N9, Q9DAG3
      Conserved Domains (1) summary
      TIGR02168
      Location:17 → 203
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    3. NM_001374039.1 → NP_001360968.1  coiled-coil domain-containing protein 172 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC158904
      Related
      ENSMUSP00000158558.2, ENSMUST00000235305.2
      Conserved Domains (1) summary
      TIGR02168
      Location:17 → 183
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    4. NM_029372.3 → NP_083648.1  coiled-coil domain-containing protein 172 isoform 1

      See identical proteins and their annotated locations for NP_083648.1

      Status: VALIDATED

      Source sequence(s)
      AC158904
      Consensus CDS
      CCDS38029.1
      UniProtKB/Swiss-Prot
      Q810N9, Q9DAG3
      Related
      ENSMUSP00000068972.7, ENSMUST00000069419.8
      Conserved Domains (1) summary
      TIGR02168
      Location:17 → 203
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      58500416..58546504
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527422.2 → XP_006527485.1  coiled-coil domain-containing protein 172 isoform X1

      Conserved Domains (1) summary
      TIGR02168
      Location:100 → 300
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    2. XM_017318304.1 → XP_017173793.1  coiled-coil domain-containing protein 172 isoform X3

      Conserved Domains (1) summary
      pfam15898
      Location:109 → 165
      PRKG1_interact; cGMP-dependent protein kinase interacting domain

    3. XM_006527423.1 → XP_006527486.1  coiled-coil domain-containing protein 172 isoform X2

      Conserved Domains (1) summary
      TIGR02168
      Location:100 → 286
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RNA

    1. XR_004940180.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q810N9.1 GenPept UniProtKB/Swiss-Prot:Q810N9

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