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    row-1 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172928, updated on 9-Dec-2024

    Summary

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    Official Symbol
    row-1
    Official Full Name
    C2H2-type domain-containing protein
    Primary source
    WormBase:WBGene00009508
    Locus tag
    CELE_F37D6.2
    See related
    AllianceGenome:WB:WBGene00009508
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including ZNF280A (zinc finger protein 280A); ZNF280B (zinc finger protein 280B); and ZNF280C (zinc finger protein 280C). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See row-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003279.8 (10475519..10478129, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Osteoclast-stimulating factor 1 Neighboring gene SKA complex subunit 1 Neighboring gene Dynein light chain Neighboring gene BRCT domain-containing protein Neighboring gene BED-type domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. H3K23me2 is a new heterochromatic mark in Caenorhabditis elegans. Vandamme J, et al. Nucleic Acids Res, 2015 Nov 16. PMID 26476455, Free PMC Article
    2. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    C2H2-type domain-containing protein
    NP_001122473.1
    • Confirmed by transcript evidence
    NP_492741.1
    • Confirmed by transcript evidence
    NP_492742.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      10475519..10478129 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060340.7 → NP_492741.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492741.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20130
      Conserved Domains (2) summary
      COG5641
      Location:15 → 288
      GAT1; GATA Zn-finger-containing transcription factor [Transcription]
      sd00017
      Location:244 → 265
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. NM_060341.5 → NP_492742.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492742.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8WQF4
      Conserved Domains (1) summary
      sd00017
      Location:243 → 264
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. NM_001129001.5 → NP_001122473.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122473.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5JYT9
      Conserved Domains (2) summary
      COG5641
      Location:15 → 288
      GAT1; GATA Zn-finger-containing transcription factor [Transcription]
      sd00017
      Location:244 → 265
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
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