Tcf/Lef HMG protein Tcf/Lef [Strongylocentrotus purpuratus (purple sea urchin)] - Gene

Summary

Gene symbol: Tcf/Lef
Gene description: HMG protein Tcf/Lef
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Strongylocentrotus purpuratus
Lineage: Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae; Strongylocentrotus
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Genomic context

Location:: chromosome: Un

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
102	current	Spur_5.0 (GCF_000002235.5)	Unplaced Scaffold	NW_022145595.1 (16556749..16574496)
Build 3.1	previous assembly	Spur_3.1 (GCF_000002235.3)	Unplaced Scaffold	NW_003577098.1 (50840..182907)

NW_022145595.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of beta-catenin-TCF complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: HMG protein Tcf/Lef

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_214475.2 → NP_999640.1 HMG protein Tcf/Lef

See identical proteins and their annotated locations for NP_999640.1

Status: PROVISIONAL

Source sequence(s)

AF161594

UniProtKB/TrEMBL

Q9Y0B2

Conserved Domains (2) summary

cd01388
Location:315 → 386

SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...

pfam08347
Location:1 → 219

CTNNB1_binding; N-terminal CTNNB1 binding