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    SPCA testis secretory pathway calcium transporting ATPase [ Strongylocentrotus purpuratus (purple sea urchin) ]

    Gene ID: 577733, updated on 14-Dec-2023

    Summary

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    Gene symbol
    SPCA
    Gene description
    testis secretory pathway calcium transporting ATPase
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Strongylocentrotus purpuratus
    Lineage
    Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae; Strongylocentrotus
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    Genomic context

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    See SPCA in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    102 current Spur_5.0 (GCF_000002235.5) Unplaced Scaffold NW_022145614.1 (23352424..23385820)
    Build 3.1 previous assembly Spur_3.1 (GCF_000002235.3) Unplaced Scaffold NW_003577170.1 (343228..375018, complement)

    NW_022145614.1Genomic Context describing neighboring genes Neighboring gene scavenger receptor cysteine-rich domain-containing group B protein Neighboring gene N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase-like Neighboring gene transmembrane protein 42-like Neighboring gene N-terminal EF-hand calcium-binding protein 1-like Neighboring gene borealin-like Neighboring gene uncharacterized LOC115920185

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evidence for a secretory pathway Ca2+-ATPase in sea urchin spermatozoa. Gunaratne HJ, et al. FEBS Lett, 2006 Jul 10. PMID 16797550
    2. Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis. Tu Q, et al. Genome Res, 2012 Oct. PMID 22709795, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables P-type calcium transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in manganese ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    testis secretory pathway calcium transporting ATPase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033649.1 → NP_001028821.1  testis secretory pathway calcium transporting ATPase

      See identical proteins and their annotated locations for NP_001028821.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ150587
      UniProtKB/TrEMBL
      Q3Y9I7
      Conserved Domains (6) summary
      cd01427
      Location:543 → 656
      HAD_like; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...
      TIGR01522
      Location:21 → 896
      ATPase-IIA2_Ca; golgi membrane calcium-translocating P-type ATPase
      pfam00122
      Location:100 → 329
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:721 → 893
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam00690
      Location:21 → 75
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      pfam13246
      Location:400 → 488
      Cation_ATPase; Cation transport ATPase (P-type)

    RefSeqs of Annotated Genomes: Strongylocentrotus purpuratus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Spur_5.0 Primary Assembly

    Genomic

    1. NW_022145614.1 Reference Spur_5.0 Primary Assembly

      Range
      23352424..23385820
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030975048.1 → XP_030830908.1  testis secretory pathway calcium transporting ATPase isoform X1

      UniProtKB/TrEMBL
      A0A7M7N476
      Conserved Domains (1) summary
      cd02085
      Location:38 → 885
      P-type_ATPase_SPCA; golgi-associated secretory pathway Ca(2+) transport ATPases, similar to human ATPase secretory pathway Ca(2+) transporting 1/hSPCA1 and Saccharomyces cerevisiae Ca(2+)/Mn(2+)-transporting P-type ATPase, Pmr1p
    Nucleotide Protein
    Heading Accession and Version

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