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    his-58 putative histone H2B 4 [ Caenorhabditis elegans ]

    Gene ID: 186251, updated on 2-Nov-2024

    Summary

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    Official Symbol
    his-58
    Official Full Name
    putative histone H2B 4
    Primary source
    WormBase:WBGene00001932
    Locus tag
    CELE_F54E12.4
    See related
    AllianceGenome:WB:WBGene00001932
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is expressed in sperm and spermatid. Orthologous to several human genes including H2BC1 (H2B clustered histone 1); H2BC10 (H2B clustered histone 10); and H2BC11 (H2B clustered histone 11). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See his-58 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_003282.8 (11339735..11340106, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Histone H3 Neighboring gene Histone H4 Neighboring gene Histone H2A Neighboring gene Kinesin-like protein klp-12 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crossing two sperm chromatin-localized mCherry transgenes into a single C. elegans strain boosts signal intensity without harming sperm function. Wong A, et al. MicroPubl Biol, 2020 Feb 12. PMID 32550502, Free PMC Article
    2. Spindle dynamics and the role of gamma-tubulin in early Caenorhabditis elegans embryos. Strome S, et al. Mol Biol Cell, 2001 Jun. PMID 11408582, Free PMC Article
    3. DamID identifies targets of CEH-60/PBX that are associated with neuron development and muscle structure in Caenorhabditis elegans. Van de Walle P, et al. PLoS One, 2020. PMID 33306687, Free PMC Article
    4. Targeted and Random Transposon-Assisted Single-Copy Transgene Insertion in C. elegans. El Mouridi S, et al. Methods Mol Biol, 2022. PMID 35320568
    5. LST-1 is a bifunctional regulator that feeds back on Notch-dependent transcription to regulate C. elegans germline stem cells. Ferdous AS, et al. Proc Natl Acad Sci U S A, 2023 Sep 26. PMID 37729202, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative histone H2B 4
    NP_502140.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11339735..11340106 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069739.7 → NP_502140.1  putative histone H2B 4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502140.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q27876
      Conserved Domains (1) summary
      smart00427
      Location:25 → 121
      H2B; Histone H2B
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q27876.3

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