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    abcf-2 ABC transporter domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176771, updated on 9-Dec-2024

    Summary

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    Official Symbol
    abcf-2
    Official Full Name
    ABC transporter domain-containing protein
    Primary source
    WormBase:WBGene00012097
    Locus tag
    CELE_T27E9.7
    See related
    AllianceGenome:WB:WBGene00012097
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ATP binding activity. Is expressed in excretory cell; head; hypodermis; intestine; and pharynx. Orthologous to human ABCF2-H2BK1 (ABCF2-H2BK1 readthrough) and ABCF2 (ATP binding cassette subfamily F member 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See abcf-2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (13457687..13462238, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene MIP18 family protein F45G2.10 Neighboring gene P-type Cu(+) transporter Neighboring gene Major sperm protein Neighboring gene Cytochrome b-c1 complex subunit 6 Neighboring gene ADP/ATP translocase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. ATP-binding cassette transporters are required for efficient RNA interference in Caenorhabditis elegans. Sundaram P, et al. Mol Biol Cell, 2006 Aug. PMID 16723499, Free PMC Article
    2. Caenorhabditis elegans ABCRNAi transporters interact genetically with rde-2 and mut-7. Sundaram P, et al. Genetics, 2008 Feb. PMID 18245353, Free PMC Article
    3. The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy. Sewell AK, et al. iScience, 2022 May 20. PMID 35479415, Free PMC Article
    4. DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans. Suen KM, et al. Nat Commun, 2020 Aug 25. PMID 32843637, Free PMC Article
    5. Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal. Zinovyeva AY, et al. Proc Natl Acad Sci U S A, 2015 Sep 22. PMID 26351692, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ABC transporter domain-containing protein
    NP_499779.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      13457687..13462238 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067378.5 → NP_499779.1  ABC transporter domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499779.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFG4
      Conserved Domains (3) summary
      cd03221
      Location:394 → 588
      ABCF_EF-3; ATP-binding cassette domain of elongation factor 3, subfamily F
      COG0488
      Location:83 → 601
      Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]
      pfam12848
      Location:294 → 364
      ABC_tran_Xtn; ABC transporter
    Nucleotide Protein
    Heading Accession and Version

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