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    poll polymerase (DNA) lambda [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100101731, updated on 14-Nov-2024

    Summary

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    Official Symbol
    pollprovided by Xenbase
    Official Full Name
    polymerase (DNA) lambdaprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-492709
    See related
    Ensembl:ENSXETG00000032755 AllianceGenome:Xenbase:XB-GENE-492709
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    beta-n; pol-kappa
    Summary
    Predicted to enable DNA binding activity; DNA-directed DNA polymerase activity; and metal ion binding activity. Predicted to act upstream of or within DNA biosynthetic process and DNA repair. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See poll in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 7 NC_030683.2 (30763985..30781498, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 7 NC_030683.1 (22462522..22482196, complement)

    Chromosome 7 - NC_030683.2Genomic Context describing neighboring genes Neighboring gene solute carrier family 2, facilitated glucose transporter member 9 like Neighboring gene uncharacterized LOC101731243 Neighboring gene deleted in a mouse model of primary ciliary dyskinesia Neighboring gene F-box and WD repeat domain containing 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-directed DNA polymerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-directed DNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in double-strand break repair via nonhomologous end joining IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA polymerase lambda
    Names
    polymerase (DNA directed), lambda
    NP_001093716.1
    XP_031760598.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100246.1 → NP_001093716.1  DNA polymerase lambda

      See identical proteins and their annotated locations for NP_001093716.1

      Status: PROVISIONAL

      Source sequence(s)
      BC135821
      UniProtKB/TrEMBL
      A0A6I8PS33, A4II30
      Related
      ENSXETP00000060859.2, ENSXETT00000062701.3
      Conserved Domains (2) summary
      cd00141
      Location:257 → 575
      NT_POLXc; Nucleotidyltransferase (NT) domain of family X DNA Polymerases
      cd17715
      Location:40 → 124
      BRCT_polymerase_lambda; BRCT domain of DNA polymerase lambda and similar proteins

    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030683.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      30763985..30781498 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031904738.1 → XP_031760598.1  DNA polymerase lambda isoform X1

      UniProtKB/TrEMBL
      A0A6I8PS33, A4II30
      Conserved Domains (2) summary
      cd00141
      Location:257 → 575
      NT_POLXc; Nucleotidyltransferase (NT) domain of family X DNA Polymerases
      cd17715
      Location:40 → 124
      BRCT_polymerase_lambda; BRCT domain of DNA polymerase lambda and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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