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    ints11 integrator complex subunit 11 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100379959, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ints11provided by Xenbase
    Official Full Name
    integrator complex subunit 11provided by Xenbase
    Primary source
    Xenbase:XB-GENE-974122
    See related
    Ensembl:ENSXETG00000030716 AllianceGenome:Xenbase:XB-GENE-974122
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Also known as
    cpsf3l
    Summary
    Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with motor and language delay, ocular defects, and brain abnormalities. Orthologous to human INTS11 (integrator complex subunit 11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ints11 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 7 NC_030683.2 (93136420..93161030)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 7 NC_030683.1 (69907491..69924592, complement)

    Chromosome 7 - NC_030683.2Genomic Context describing neighboring genes Neighboring gene dishevelled segment polarity protein 1 Neighboring gene ceramide-1-phosphate transfer protein Neighboring gene speedy protein 1-B-like Neighboring gene provisional ortholog of lysophosphatidic acid receptor 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    integrator complex subunit 11
    Names
    cleavage and polyadenylation specific factor 3-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030683.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      93136420..93161030
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031905599.1 → XP_031761459.1  integrator complex subunit 11

      UniProtKB/TrEMBL
      A0A6I8PNB8, A0A6I8QS19
      Related
      ENSXETP00000058356.3, ENSXETT00000064070.3
      Conserved Domains (2) summary
      COG1236
      Location:4 → 431
      YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
      cd16291
      Location:6 → 204
      INTS11-like_MBL-fold; Integrator complex subunit 11, and related proteins; MBL-fold metallo-hydrolase domain

    2. XM_031905601.1 → XP_031761461.1  integrator complex subunit 11

      UniProtKB/TrEMBL
      A0A6I8PNB8, A0A6I8QS19
      Conserved Domains (2) summary
      COG1236
      Location:4 → 431
      YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
      cd16291
      Location:6 → 204
      INTS11-like_MBL-fold; Integrator complex subunit 11, and related proteins; MBL-fold metallo-hydrolase domain

    3. XM_031905600.1 → XP_031761460.1  integrator complex subunit 11

      UniProtKB/TrEMBL
      A0A6I8PNB8, A0A6I8QS19
      Conserved Domains (2) summary
      COG1236
      Location:4 → 431
      YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
      cd16291
      Location:6 → 204
      INTS11-like_MBL-fold; Integrator complex subunit 11, and related proteins; MBL-fold metallo-hydrolase domain
    Nucleotide Protein Strain
    Heading Accession and Version

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