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    klhl21 kelch like family member 21 [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100495738, updated on 9-Dec-2024

    Summary

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    Official Symbol
    klhl21provided by Xenbase
    Official Full Name
    kelch like family member 21provided by Xenbase
    Primary source
    Xenbase:XB-GENE-5802687
    See related
    Ensembl:ENSXETG00000011114 AllianceGenome:Xenbase:XB-GENE-5802687
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to act upstream of or within cell division and protein ubiquitination. Predicted to be located in cytoplasm and spindle. Orthologous to human KLHL21 (kelch like family member 21). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See klhl21 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 7 NC_030683.2 (99596730..99629837, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 7 NC_030683.1 (91400963..91433378, complement)

    Chromosome 7 - NC_030683.2Genomic Context describing neighboring genes Neighboring gene hairy and enhancer of split 5 gene 10 Neighboring gene zinc finger and BTB domain containing 48 Neighboring gene PHD finger protein 13 Neighboring gene DnaJ heat shock protein family (Hsp40) member C11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ubiquitin-like ligase-substrate adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul3-RING ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    kelch-like protein 21

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030683.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      99596730..99629837 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004916197.4 → XP_004916254.1  kelch-like protein 21

      See identical proteins and their annotated locations for XP_004916254.1

      UniProtKB/TrEMBL
      F6VUC8
      Conserved Domains (4) summary
      PHA03098
      Location:43 → 557
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:336 → 378
      Kelch; KELCH repeat [structural motif]
      cd18250
      Location:25 → 148
      BTB_POZ_KLHL21; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 21 (KLHL21)
      cd18460
      Location:143 → 243
      BACK_KLHL21; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 21 (KLHL21)

    2. XM_004916194.4 → XP_004916251.1  kelch-like protein 21

      See identical proteins and their annotated locations for XP_004916251.1

      UniProtKB/TrEMBL
      F6VUC8
      Conserved Domains (4) summary
      PHA03098
      Location:43 → 557
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:336 → 378
      Kelch; KELCH repeat [structural motif]
      cd18250
      Location:25 → 148
      BTB_POZ_KLHL21; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 21 (KLHL21)
      cd18460
      Location:143 → 243
      BACK_KLHL21; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 21 (KLHL21)

    3. XM_002933852.5 → XP_002933898.2  kelch-like protein 21

      See identical proteins and their annotated locations for XP_002933898.2

      UniProtKB/TrEMBL
      F6VUC8
      Related
      ENSXETP00000024281.4, ENSXETT00000024281.4
      Conserved Domains (4) summary
      PHA03098
      Location:43 → 557
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:336 → 378
      Kelch; KELCH repeat [structural motif]
      cd18250
      Location:25 → 148
      BTB_POZ_KLHL21; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 21 (KLHL21)
      cd18460
      Location:143 → 243
      BACK_KLHL21; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 21 (KLHL21)

    4. XM_031905611.1 → XP_031761471.1  kelch-like protein 21

      UniProtKB/TrEMBL
      F6VUC8
      Conserved Domains (4) summary
      PHA03098
      Location:43 → 557
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:336 → 378
      Kelch; KELCH repeat [structural motif]
      cd18250
      Location:25 → 148
      BTB_POZ_KLHL21; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 21 (KLHL21)
      cd18460
      Location:143 → 243
      BACK_KLHL21; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 21 (KLHL21)

    5. XM_004916195.4 → XP_004916252.1  kelch-like protein 21

      See identical proteins and their annotated locations for XP_004916252.1

      UniProtKB/TrEMBL
      F6VUC8
      Conserved Domains (4) summary
      PHA03098
      Location:43 → 557
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:336 → 378
      Kelch; KELCH repeat [structural motif]
      cd18250
      Location:25 → 148
      BTB_POZ_KLHL21; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 21 (KLHL21)
      cd18460
      Location:143 → 243
      BACK_KLHL21; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 21 (KLHL21)
    Nucleotide Protein Strain
    Heading Accession and Version

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