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    cnksr2a connector enhancer of kinase suppressor of Ras 2a [ Clupea harengus (Atlantic herring) ]

    Gene ID: 105893729, updated on 19-Nov-2024

    Summary

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    Gene symbol
    cnksr2a
    Gene description
    connector enhancer of kinase suppressor of Ras 2a
    See related
    Ensembl:ENSCHAG00020006013
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Clupea harengus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Clupei; Clupeiformes; Clupeoidei; Clupeidae; Clupea
    Also known as
    cnksr2
    Orthologs
    zebrafish all
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    Genomic context

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    See cnksr2a in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    102 current Ch_v2.0.2 (GCF_900700415.2) 17 NC_045168.1 (21989420..22073147)

    Chromosome 17 - NC_045168.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116224450 Neighboring gene uncharacterized LOC122133673 Neighboring gene kelch-like protein 34 Neighboring gene small muscle protein X-linked

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_045168.1 Chromosome 17 Reference Ch_v2.0.2 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    connector enhancer of kinase suppressor of ras 2
    Names
    connector enhancer of kinase suppressor of Ras 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Clupea harengus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Ch_v2.0.2 Primary Assembly

    Genomic

    1. NC_045168.1 Reference Ch_v2.0.2 Primary Assembly

      Range
      21989420..22073147
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_031583930.2 → XP_031439790.1  connector enhancer of kinase suppressor of ras 2 isoform X1

      UniProtKB/TrEMBL
      A0A6P8GYD8
      Related
      ENSCHAP00020012326.1, ENSCHAT00020013223.1
      Conserved Domains (5) summary
      cd09511
      Location:8 → 76
      SAM_CNK1,2,3-suppressor; SAM domain of CNK1,2,3-suppressor subfamily
      cd01260
      Location:578 → 691
      PH_CNK_mammalian-like; Connector enhancer of KSR (Kinase suppressor of ras) (CNK) pleckstrin homology (PH) domain
      pfam06663
      Location:346 → 531
      DUF1170; Protein of unknown function (DUF1170)
      pfam10534
      Location:84 → 182
      CRIC_ras_sig; Connector enhancer of kinase suppressor of ras
      cl00117
      Location:231 → 301
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

    2. XM_031583931.2 → XP_031439791.1  connector enhancer of kinase suppressor of ras 2 isoform X2

      UniProtKB/TrEMBL
      A0A6P8GPV7
      Conserved Domains (5) summary
      cd09511
      Location:8 → 76
      SAM_CNK1,2,3-suppressor; SAM domain of CNK1,2,3-suppressor subfamily
      cd01260
      Location:577 → 690
      PH_CNK_mammalian-like; Connector enhancer of KSR (Kinase suppressor of ras) (CNK) pleckstrin homology (PH) domain
      pfam06663
      Location:346 → 531
      DUF1170; Protein of unknown function (DUF1170)
      pfam10534
      Location:84 → 182
      CRIC_ras_sig; Connector enhancer of kinase suppressor of ras
      cl00117
      Location:231 → 301
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

    3. XM_031583934.2 → XP_031439794.1  connector enhancer of kinase suppressor of ras 2 isoform X5

      UniProtKB/TrEMBL
      A0A6P8GL20
      Conserved Domains (5) summary
      cd09511
      Location:8 → 76
      SAM_CNK1,2,3-suppressor; SAM domain of CNK1,2,3-suppressor subfamily
      cd00992
      Location:228 → 276
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd01260
      Location:529 → 642
      PH_CNK_mammalian-like; Connector enhancer of KSR (Kinase suppressor of ras) (CNK) pleckstrin homology (PH) domain
      pfam06663
      Location:297 → 482
      DUF1170; Protein of unknown function (DUF1170)
      pfam10534
      Location:84 → 182
      CRIC_ras_sig; Connector enhancer of kinase suppressor of ras

    4. XM_031583932.2 → XP_031439792.1  connector enhancer of kinase suppressor of ras 2 isoform X3

      UniProtKB/TrEMBL
      A0A6P8GWE1
      Related
      ENSCHAP00020012333.1, ENSCHAT00020013230.1
      Conserved Domains (5) summary
      cd09511
      Location:8 → 76
      SAM_CNK1,2,3-suppressor; SAM domain of CNK1,2,3-suppressor subfamily
      cd01260
      Location:572 → 685
      PH_CNK_mammalian-like; Connector enhancer of KSR (Kinase suppressor of ras) (CNK) pleckstrin homology (PH) domain
      pfam06663
      Location:340 → 525
      DUF1170; Protein of unknown function (DUF1170)
      pfam10534
      Location:84 → 176
      CRIC_ras_sig; Connector enhancer of kinase suppressor of ras
      cl00117
      Location:225 → 295
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

    5. XM_031583933.2 → XP_031439793.1  connector enhancer of kinase suppressor of ras 2 isoform X4

      UniProtKB/TrEMBL
      A0A6P8GLJ7
      Related
      ENSCHAP00020012330.1, ENSCHAT00020013227.1
      Conserved Domains (5) summary
      cd09511
      Location:8 → 76
      SAM_CNK1,2,3-suppressor; SAM domain of CNK1,2,3-suppressor subfamily
      cd01260
      Location:571 → 684
      PH_CNK_mammalian-like; Connector enhancer of KSR (Kinase suppressor of ras) (CNK) pleckstrin homology (PH) domain
      pfam06663
      Location:340 → 525
      DUF1170; Protein of unknown function (DUF1170)
      pfam10534
      Location:84 → 176
      CRIC_ras_sig; Connector enhancer of kinase suppressor of ras
      cl00117
      Location:225 → 295
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...

    6. XM_031583935.2 → XP_031439795.1  connector enhancer of kinase suppressor of ras 2 isoform X6

      UniProtKB/TrEMBL
      A0A6P8GYE4
      Related
      ENSCHAP00020012337.1, ENSCHAT00020013234.1
      Conserved Domains (5) summary
      cd09511
      Location:8 → 76
      SAM_CNK1,2,3-suppressor; SAM domain of CNK1,2,3-suppressor subfamily
      cd00992
      Location:222 → 270
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd01260
      Location:523 → 636
      PH_CNK_mammalian-like; Connector enhancer of KSR (Kinase suppressor of ras) (CNK) pleckstrin homology (PH) domain
      pfam06663
      Location:291 → 476
      DUF1170; Protein of unknown function (DUF1170)
      pfam10534
      Location:84 → 176
      CRIC_ras_sig; Connector enhancer of kinase suppressor of ras

    7. XM_031583936.2 → XP_031439796.1  connector enhancer of kinase suppressor of ras 2 isoform X7

      UniProtKB/TrEMBL
      A0A6P8GPW3
      Related
      ENSCHAP00020012340.1, ENSCHAT00020013237.1
      Conserved Domains (5) summary
      cd09511
      Location:8 → 76
      SAM_CNK1,2,3-suppressor; SAM domain of CNK1,2,3-suppressor subfamily
      cd00992
      Location:222 → 270
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd01260
      Location:522 → 635
      PH_CNK_mammalian-like; Connector enhancer of KSR (Kinase suppressor of ras) (CNK) pleckstrin homology (PH) domain
      pfam06663
      Location:291 → 476
      DUF1170; Protein of unknown function (DUF1170)
      pfam10534
      Location:84 → 176
      CRIC_ras_sig; Connector enhancer of kinase suppressor of ras
    Nucleotide Protein
    Heading Accession and Version

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