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    ganab glucosidase, alpha; neutral AB [ Xenopus tropicalis (tropical clawed frog) ]

    Gene ID: 100492576, updated on 4-Nov-2024

    Summary

    Official Symbol
    ganabprovided by Xenbase
    Official Full Name
    glucosidase, alpha; neutral ABprovided by Xenbase
    Primary source
    Xenbase:XB-GENE-997256
    See related
    Ensembl:ENSXETG00000005580 AllianceGenome:Xenbase:XB-GENE-997256
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Xenopus tropicalis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
    Summary
    Predicted to enable alpha-glucosidase activity and carbohydrate binding activity. Predicted to act upstream of or within carbohydrate metabolic process. Human ortholog(s) of this gene implicated in polycystic kidney disease; polycystic kidney disease 3; and polycystic liver disease. Orthologous to human GANAB (glucosidase II alpha subunit). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See ganab in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (36923566..36956848, complement)
    103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (41622129..41654001, complement)

    Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene retinal outer segment membrane protein 1 Neighboring gene beta-1,3-glucuronyltransferase 3 Neighboring gene small nucleolar RNA SNORD31 Neighboring gene integrator complex subunit 5

    Genomic regions, transcripts, and products

    General protein information

    Preferred Names
    neutral alpha-glucosidase AB

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference UCB_Xtro_10.0 Primary Assembly

    Genomic

    1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

      Range
      36923566..36956848 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002942977.5XP_002943023.3  neutral alpha-glucosidase AB isoform X2

      UniProtKB/TrEMBL
      A0A6I8R1G1, A0A8J0QZ98
      Related
      ENSXETP00000075822.2, ENSXETT00000073713.2
      Conserved Domains (2) summary
      cd06603
      Location:398865
      GH31_GANC_GANAB_alpha; neutral alpha-glucosidase C, neutral alpha-glucosidase AB
      cd14752
      Location:258398
      GH31_N; N-terminal domain of glycosyl hydrolase family 31 (GH31)
    2. XM_004919701.4XP_004919758.2  neutral alpha-glucosidase AB isoform X1

      UniProtKB/TrEMBL
      A0A6I8QIB2, A0A8J0R8J0
      Related
      ENSXETP00000072043.2, ENSXETT00000076410.2
      Conserved Domains (2) summary
      cd06603
      Location:420887
      GH31_GANC_GANAB_alpha; neutral alpha-glucosidase C, neutral alpha-glucosidase AB
      cd14752
      Location:280420
      GH31_N; N-terminal domain of glycosyl hydrolase family 31 (GH31)