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    GRK7 G protein-coupled receptor kinase 7 [ Bos taurus (domestic cattle) ]

    Gene ID: 281802, updated on 27-Dec-2024

    Summary

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    Official Symbol
    GRK7provided by VGNC
    Official Full Name
    G protein-coupled receptor kinase 7provided by VGNC
    Primary source
    VGNC:VGNC:29658
    See related
    BGD:BT15246; Ensembl:ENSBTAG00000021886
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    GPRK7
    Orthologs
    human all
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    Genomic context

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    See GRK7 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (127145166..127185456, complement)

    Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene small ribosomal subunit protein eS12 Neighboring gene ATPase Na+/K+ transporting subunit beta 3 Neighboring gene uncharacterized LOC112448292 Neighboring gene ring finger protein 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Characterization of human GRK7 as a potential cone opsin kinase. Chen CK, et al. Mol Vis, 2001 Dec 21. PMID 11754336
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables rhodopsin kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rhodopsin kinase GRK7
    Names
    g protein-coupled receptor kinase GRK7
    NP_776757.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174332.3 → NP_776757.1  rhodopsin kinase GRK7

      See identical proteins and their annotated locations for NP_776757.1

      Status: PROVISIONAL

      Source sequence(s)
      AY049726
      UniProtKB/Swiss-Prot
      Q8WMV0
      Related
      ENSBTAP00000029175.4, ENSBTAT00000029175.5
      Conserved Domains (2) summary
      cd05607
      Location:188 → 474
      STKc_GRK7; Catalytic domain of the Protein Serine/Threonine Kinase, G protein-coupled Receptor Kinase 7
      cl02565
      Location:40 → 181
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      127145166..127185456 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8WMV0.1 GenPept UniProtKB/Swiss-Prot:Q8WMV0

    Gene LinkOut

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    Research Materials