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    APLP1 amyloid beta precursor like protein 1 [ Thamnophis elegans (Western terrestrial garter snake) ]

    Gene ID: 116515907, updated on 18-Mar-2024

    Summary

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    Gene symbol
    APLP1
    Gene description
    amyloid beta precursor like protein 1
    See related
    EnsemblRapid:ENSTELG00000006779
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Thamnophis elegans
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Colubridae; Natricinae; Thamnophis
    Orthologs
    human mouse all
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    Genomic context

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    See APLP1 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    100 current rThaEle1.pri (GCF_009769535.1) 12 NC_045552.1 (11525155..11583784)

    Chromosome 12 - NC_045552.1Genomic Context describing neighboring genes Neighboring gene NPHS1 adhesion molecule, nephrin Neighboring gene kirre like nephrin family adhesion molecule 2 Neighboring gene uroplakin 1A Neighboring gene Rho GTPase activating protein 33

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_045552.1 Chromosome 12 Reference rThaEle1.pri

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables alpha-2A adrenergic receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables alpha-2B adrenergic receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables alpha-2C adrenergic receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables heparin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transition metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in central nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    amyloid-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Thamnophis elegans Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference rThaEle1.pri

    Genomic

    1. NC_045552.1 Reference rThaEle1.pri

      Range
      11525155..11583784
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_032228214.1 → XP_032084105.1  amyloid-like protein 1 isoform X1

      Conserved Domains (3) summary
      smart00006
      Location:49 → 208
      A4_EXTRA; amyloid A4
      pfam12925
      Location:335 → 517
      APP_E2; E2 domain of amyloid precursor protein
      cd21708
      Location:624 → 708
      JMTM_APLP1; juxtamembrane and transmembrane (JMTM) domain found in amyloid-like protein 1 (APLP-1) and similar proteins

    2. XM_032228215.1 → XP_032084106.1  amyloid-like protein 1 isoform X2

      Related
      ENSTELP00000009553.1, ENSTELT00000010056.1
      Conserved Domains (3) summary
      smart00006
      Location:49 → 208
      A4_EXTRA; amyloid A4
      pfam12925
      Location:335 → 517
      APP_E2; E2 domain of amyloid precursor protein
      cd21708
      Location:616 → 700
      JMTM_APLP1; juxtamembrane and transmembrane (JMTM) domain found in amyloid-like protein 1 (APLP-1) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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