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    LOC5510773 bone morphogenetic protein 2 [ Nematostella vectensis (starlet sea anemone) ]

    Gene ID: 5510773, updated on 3-Dec-2024

    Summary

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    Gene symbol
    LOC5510773
    Gene description
    bone morphogenetic protein 2
    Locus tag
    NEMVEDRAFT_v1g168498
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Nematostella vectensis
    Lineage
    Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria; Edwardsiidae; Nematostella
    Also known as
    BMP2/4
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    Genomic context

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    See LOC5510773 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    101 current jaNemVect1.1 (GCF_932526225.1) 7 NC_064040.1 (12244530..12258278)
    100 previous assembly ASM20922v1 (GCF_000209225.1) Unplaced Scaffold NW_001834308.1 (416828..430900)

    Chromosome 7 - NC_064040.1Genomic Context describing neighboring genes Neighboring gene MAP3K12-binding inhibitory protein 1 Neighboring gene visual system homeobox 2 Neighboring gene BTB/POZ domain-containing protein 9 Neighboring gene uncharacterized LOC116617320 Neighboring gene ATP-binding cassette sub-family B member 10, mitochondrial Neighboring gene melatonin receptor type 1B-B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequential actions of β-catenin and Bmp pattern the oral nerve net in Nematostella vectensis. Watanabe H, et al. Nat Commun, 2014 Dec 23. PMID 25534229, Free PMC Article
    2. Asymmetric expression of the BMP antagonists chordin and gremlin in the sea anemone Nematostella vectensis: implications for the evolution of axial patterning. Rentzsch F, et al. Dev Biol, 2006 Aug 15. PMID 16828077
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. beta-catenin and Bmp signalling are involved in the formation of the cnidarian oral nervous system.
      Title: Sequential actions of β-catenin and Bmp pattern the oral nerve net in Nematostella vectensis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bone morphogenetic protein 2
    Names
    decapentaplegic-like protein
    predicted protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Nematostella vectensis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference jaNemVect1.1

    Genomic

    1. NC_064040.1 Reference jaNemVect1.1

      Range
      12244530..12258278
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_048729994.1 → XP_048585951.1  bone morphogenetic protein 2 isoform X2

      UniProtKB/TrEMBL
      A7SAY4, Q5YJC4

    2. XM_032379936.2 → XP_032235827.1  bone morphogenetic protein 2 isoform X2

      UniProtKB/TrEMBL
      A7SAY4, Q5YJC4
      Conserved Domains (2) summary
      cl40434
      Location:277 → 377
      TGF_beta_SF; transforming growth factor beta (TGF-beta) like domain found in TGF-beta superfamily
      pfam00688
      Location:22 → 248
      TGFb_propeptide; TGF-beta propeptide

    3. XM_048729992.1 → XP_048585949.1  bone morphogenetic protein 2 isoform X2

      UniProtKB/TrEMBL
      A7SAY4, Q5YJC4

    4. XM_032379937.2 → XP_032235828.1  bone morphogenetic protein 2 isoform X2

      UniProtKB/TrEMBL
      A7SAY4, Q5YJC4
      Conserved Domains (2) summary
      cl40434
      Location:277 → 377
      TGF_beta_SF; transforming growth factor beta (TGF-beta) like domain found in TGF-beta superfamily
      pfam00688
      Location:22 → 248
      TGFb_propeptide; TGF-beta propeptide

    5. XM_048729993.1 → XP_048585950.1  bone morphogenetic protein 2 isoform X2

      UniProtKB/TrEMBL
      A7SAY4, Q5YJC4

    6. XM_032379935.2 → XP_032235826.1  bone morphogenetic protein 2 isoform X1

      UniProtKB/TrEMBL
      Q5YJC4
      Conserved Domains (2) summary
      cl40434
      Location:327 → 427
      TGF_beta_SF; transforming growth factor beta (TGF-beta) like domain found in TGF-beta superfamily
      pfam00688
      Location:72 → 298
      TGFb_propeptide; TGF-beta propeptide
    Nucleotide Protein
    Heading Accession and Version

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