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    SOCS4 suppressor of cytokine signaling 4 [ Phoca vitulina (harbor seal) ]

    Gene ID: 116632990, updated on 18-Mar-2024

    Summary

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    Gene symbol
    SOCS4
    Gene description
    suppressor of cytokine signaling 4
    See related
    EnsemblRapid:ENSPVHG00000007860
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Phoca vitulina
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Phoca
    Orthologs
    human mouse all
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    Genomic context

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    See SOCS4 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    100 current GSC_HSeal_1.0 (GCF_004348235.1) Unplaced Scaffold NW_022589710.1 (28421466..28442073)

    NW_022589710.1Genomic Context describing neighboring genes Neighboring gene G2/mitotic-specific cyclin-B1-like Neighboring gene WD repeat and HMG-box DNA binding protein 1 Neighboring gene mitogen-activated protein kinase 1 interacting protein 1 like Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_022589710 Unplaced Scaffold Reference GSC_HSeal_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of phosphatidylinositol 3-kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    suppressor of cytokine signaling 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Phoca vitulina Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GSC_HSeal_1.0 Primary Assembly

    Genomic

    1. NW_022589710.1 Reference GSC_HSeal_1.0 Primary Assembly

      Range
      28421466..28442073
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_032405158.1 → XP_032261049.1  suppressor of cytokine signaling 4

      Related
      ENSPVHP00000009629.1, ENSPVHT00000010930.1
      Conserved Domains (3) summary
      cd10385
      Location:276 → 376
      SH2_SOCS4; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
      pfam12610
      Location:59 → 109
      SOCS; Suppressor of cytokine signalling
      cl02533
      Location:385 → 439
      SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...
    Nucleotide Protein
    Heading Accession and Version

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