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    HGF hepatocyte growth factor [ Trachypithecus francoisi (Francois's langur) ]

    Gene ID: 117072632, updated on 19-Mar-2024

    Summary

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    Gene symbol
    HGF
    Gene description
    hepatocyte growth factor
    See related
    EnsemblRapid:ENSTFRG00000027557
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Trachypithecus francoisi
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Trachypithecus
    Orthologs
    human mouse all
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    Genomic context

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    See HGF in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    100 current Tfra_2.0 (GCF_009764315.1) Unplaced Scaffold NW_022681469.1 (61649937..61720290, complement)

    NW_022681469.1Genomic Context describing neighboring genes Neighboring gene semaphorin 3C Neighboring gene desmocollin-2-like Neighboring gene uncharacterized LOC117073591 Neighboring gene calcium voltage-gated channel auxiliary subunit alpha2delta 1 Neighboring gene uncharacterized LOC117072562

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_022681469 Unplaced Scaffold Reference Tfra_2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hepatocyte growth factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Trachypithecus francoisi Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Tfra_2.0 Primary Assembly

    Genomic

    1. NW_022681469.1 Reference Tfra_2.0 Primary Assembly

      Range
      61649937..61720290 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_033192970.1 → XP_033048861.1  hepatocyte growth factor isoform X1

      Conserved Domains (4) summary
      smart00130
      Location:275 → 355
      KR; Kringle domain
      cd00108
      Location:453 → 535
      KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
      cd00129
      Location:104 → 187
      PAN_APPLE; PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth factor proteins, plasma prekallikrein/coagulation factor XI and microneme antigen proteins, plant receptor-like protein kinases, and various nematode and leech ...
      cd00190
      Location:560 → 784
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    2. XM_033192974.1 → XP_033048865.1  hepatocyte growth factor isoform X5

      Conserved Domains (4) summary
      smart00020
      Location:489 → 711
      Tryp_SPc; Trypsin-like serine protease
      smart00130
      Location:205 → 285
      KR; Kringle domain
      cd00108
      Location:383 → 465
      KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
      cd00129
      Location:39 → 122
      PAN_APPLE; PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth factor proteins, plasma prekallikrein/coagulation factor XI and microneme antigen proteins, plant receptor-like protein kinases, and various nematode and leech ...

    3. XM_033192972.1 → XP_033048863.1  hepatocyte growth factor isoform X3

      Conserved Domains (4) summary
      smart00020
      Location:554 → 776
      Tryp_SPc; Trypsin-like serine protease
      smart00130
      Location:270 → 350
      KR; Kringle domain
      cd00108
      Location:448 → 530
      KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
      cd00129
      Location:104 → 187
      PAN_APPLE; PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth factor proteins, plasma prekallikrein/coagulation factor XI and microneme antigen proteins, plant receptor-like protein kinases, and various nematode and leech ...

    4. XM_033192971.1 → XP_033048862.1  hepatocyte growth factor isoform X2

      Conserved Domains (4) summary
      smart00020
      Location:554 → 776
      Tryp_SPc; Trypsin-like serine protease
      smart00130
      Location:270 → 350
      KR; Kringle domain
      cd00108
      Location:448 → 530
      KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
      cd00129
      Location:99 → 182
      PAN_APPLE; PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth factor proteins, plasma prekallikrein/coagulation factor XI and microneme antigen proteins, plant receptor-like protein kinases, and various nematode and leech ...

    5. XM_033192973.1 → XP_033048864.1  hepatocyte growth factor isoform X4

      Related
      ENSTFRP00000032196.1, ENSTFRT00000040609.1
      Conserved Domains (4) summary
      smart00020
      Location:494 → 716
      Tryp_SPc; Trypsin-like serine protease
      smart00130
      Location:210 → 290
      KR; Kringle domain
      cd00108
      Location:388 → 470
      KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
      cd00129
      Location:39 → 122
      PAN_APPLE; PAN/APPLE-like domain; present in N-terminal (N) domains of plasminogen/ hepatocyte growth factor proteins, plasma prekallikrein/coagulation factor XI and microneme antigen proteins, plant receptor-like protein kinases, and various nematode and leech ...
    Nucleotide Protein
    Heading Accession and Version

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