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    jak3 Janus kinase 3 (a protein tyrosine kinase, leukocyte) [ Onychostoma macrolepis ]

    Gene ID: 131545882, updated on 11-Apr-2024

    Summary

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    Gene symbol
    jak3
    Gene description
    Janus kinase 3 (a protein tyrosine kinase, leukocyte)
    Locus tag
    G5714_009468
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Onychostoma macrolepis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Acrossocheilinae; Onychostoma
    Orthologs
    human zebrafish all
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    Genomic context

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    See jak3 in Genome Data Viewer
    Location:
    chromosome: 08
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2023_08 current ASM1243209v1 (GCF_012432095.1) 08 NC_081162.1 (21905441..21920577, complement)

    Chromosome 08 - NC_081162.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC131545973 Neighboring gene N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3-like Neighboring gene solute carrier family 5 member 5 Neighboring gene coiled-coil domain containing 124

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_081162.1 Chromosome 08 Reference ASM1243209v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytokine receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables non-membrane spanning protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cytokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in hemopoiesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-tyrosine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase JAK2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_012432095.1-RS_2023_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1243209v1 Primary Assembly

    Genomic

    1. NC_081162.1 Reference ASM1243209v1 Primary Assembly

      Range
      21905441..21920577 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_058785083.1 → XP_058641066.1  tyrosine-protein kinase JAK2

      UniProtKB/TrEMBL
      A0A7J6CSH5
    Nucleotide Protein
    Heading Accession and Version

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