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    N neurogenic locus Notch protein [ Drosophila guanche ]

    Gene ID: 117590461, updated on 13-May-2024

    Summary

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    Gene symbol
    N
    Gene description
    neurogenic locus Notch protein
    Locus tag
    DGUA_6G018764
    See related
    EnsemblRapid:LOC117590461
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Drosophila guanche
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Orthologs
    fruit fly all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    100 current DGUA_6 (GCF_900245975.1) Unplaced Scaffold NW_022995757.1 (449489..488427)

    NW_022995757.1Genomic Context describing neighboring genes Neighboring gene kin of irre Neighboring gene uncharacterized LOC117590285 Neighboring gene uncharacterized LOC117590226 Neighboring gene UPF0729 protein GD16342 Neighboring gene Follicle cell protein 3C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_022995757 Unplaced Scaffold Reference DGUA_6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables Notch binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of developmental process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neurogenic locus Notch protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Drosophila guanche Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference DGUA_6

    Genomic

    1. NW_022995757.1 Reference DGUA_6

      Range
      449489..488427
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_034283098.1 → XP_034138989.1  neurogenic locus Notch protein

      UniProtKB/TrEMBL
      A0A3B0K5G0
      Related
      XP_034138989.1, XM_034283098.1
      Conserved Domains (10) summary
      smart00004
      Location:1469 → 1505
      NL; Domain found in Notch and Lin-12
      COG0666
      Location:1972 → 2138
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00054
      Location:440 → 477
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      sd00045
      Location:2009 → 2040
      ANK; ANK repeat [structural motif]
      pfam00008
      Location:1055 → 1085
      EGF; EGF-like domain
      pfam00066
      Location:1556 → 1585
      Notch; LNR domain
      pfam06816
      Location:1592 → 1646
      NOD; NOTCH protein
      pfam07684
      Location:1673 → 1723
      NODP; NOTCH protein
      pfam11936
      Location:2631 → 2686
      DUF3454; Domain of unknown function (DUF3454)
      cl41775
      Location:1711 → 1798
      JMTM_Notch_APP; juxtamembrane and transmembrane (JMTM) domain found in Notch and APP family proteins
    Nucleotide Protein
    Heading Accession and Version

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