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    AGO4 argonaute RISC component 4 [ Ailuropoda melanoleuca (giant panda) ]

    Gene ID: 100465900, updated on 8-Mar-2024

    Summary

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    Gene symbol
    AGO4
    Gene description
    argonaute RISC component 4
    Locus tag
    PANDA_005372
    See related
    Ensembl:ENSAMEG00000000573
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ailuropoda melanoleuca
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda
    Also known as
    EIF2C4
    Orthologs
    human mouse all
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    Genomic context

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    See AGO4 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current ASM200744v2 (GCF_002007445.1) 2 NC_048219.1 (13665378..13703621)
    102 previous assembly AilMel_1.0 (GCF_000004335.2) Unplaced Scaffold NW_003217469.1 (369012..395876, complement)

    Chromosome 2 - NC_048219.1Genomic Context describing neighboring genes Neighboring gene claspin Neighboring gene mitochondrial import inner membrane translocase subunit Tim17-A-like Neighboring gene argonaute RISC component 1 Neighboring gene argonaute RISC catalytic component 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein argonaute-4
    Names
    argonaute 4, RISC catalytic component
    argonaute RISC catalytic component 4
    eukaryotic translation initiation factor 2C, 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Ailuropoda melanoleuca Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM200744v2 Primary Assembly

    Genomic

    1. NC_048219.1 Reference ASM200744v2 Primary Assembly

      Range
      13665378..13703621
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_034649064.1 → XP_034504955.1  protein argonaute-4 isoform X1

      UniProtKB/TrEMBL
      D2H608, G1L1F1
      Related
      ENSAMEP00000000704.2, ENSAMET00000000728.2
      Conserved Domains (4) summary
      cd02846
      Location:217 → 337
      PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
      cd04657
      Location:384 → 819
      Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...
      pfam08699
      Location:166 → 216
      ArgoL1; Argonaute linker 1 domain
      pfam16486
      Location:26 → 155
      ArgoN; N-terminal domain of argonaute

    2. XM_034649068.1 → XP_034504959.1  protein argonaute-4 isoform X2

      UniProtKB/TrEMBL
      D2H608

    3. XM_034649074.1 → XP_034504965.1  protein argonaute-4 isoform X4

      UniProtKB/TrEMBL
      D2H608

    4. XM_034649069.1 → XP_034504960.1  protein argonaute-4 isoform X3

      UniProtKB/TrEMBL
      D2H608
      Conserved Domains (4) summary
      cd02846
      Location:150 → 270
      PAZ_argonaute_like; PAZ domain, argonaute_like subfamily. Argonaute is part of the RNA-induced silencing complex (RISC), and is an endonuclease that plays a key role in the RNA interference pathway. The PAZ domain has been named after the proteins Piwi,Argonaut, and Zwille. ...
      cd04657
      Location:317 → 752
      Piwi_ago-like; PIWI domain, Argonaute-like subfamily. Argonaute is the central component of the RNA-induced silencing complex (RISC) and related complexes. The PIWI domain is the C-terminal portion of Argonaute and consists of two subdomains, one of which provides the ...
      pfam08699
      Location:99 → 149
      ArgoL1; Argonaute linker 1 domain
      pfam16486
      Location:4 → 88
      ArgoN; N-terminal domain of argonaute
    Nucleotide Protein
    Heading Accession and Version

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