cit-1.1 Cyclin-T1.1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: cit-1.1
Official Full Name: Cyclin-T1.1
Primary source: WormBase:WBGene00000507
Locus tag: CELE_F44B9.4
See related: AllianceGenome:WB:WBGene00000507
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity. Predicted to be involved in positive regulation of DNA-templated transcription, elongation and positive regulation of transcription by RNA polymerase II. Predicted to be part of cyclin/CDK positive transcription elongation factor complex. Predicted to be active in nucleus. Is expressed widely. Orthologous to several human genes including CCNT1 (cyclin T1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See cit-1.1 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 15

Sequence:: Chromosome: III; NC_003281.10 (8005933..8009821, complement)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

STS3-168 (e-PCR)
- UniSTS:242010

F44B9.4 (e-PCR)
- UniSTS:314332

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables cyclin-dependent protein serine/threonine kinase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables cyclin-dependent protein serine/threonine kinase regulator activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of DNA-templated transcription, elongation	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of cyclin/CDK positive transcription elongation factor complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Cyclin-T1.1

NP_001370392.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

8005933..8009821 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001382928.1 → NP_001370392.1 Cyclin-T1.1 [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/Swiss-Prot

P34425, Q8IG21, Q8IG22

Conserved Domains (2) summary

cd20539
Location:165 → 263

CYCLIN_CCNT_rpt2; second cyclin box found in cyclin-T (CCNT) family

cl40454
Location:19 → 160

CYCLIN_SF; Cyclin box fold superfamily