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    Niban3 niban apoptosis regulator 3 [ Mus musculus (house mouse) ]

    Gene ID: 100037278, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Niban3provided by MGI
    Official Full Name
    niban apoptosis regulator 3provided by MGI
    Primary source
    MGI:MGI:3686743
    See related
    Ensembl:ENSMUSG00000043243 AllianceGenome:MGI:3686743
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bcnp1; Fam129c
    Summary
    Orthologous to human NIBAN3 (niban apoptosis regulator 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in spleen adult (RPKM 24.5), thymus adult (RPKM 3.3) and 3 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Niban3 in Genome Data Viewer
    Location:
    8 B3.3; 8 34.43 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (72049000..72061599)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (71596356..71608146)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10508 Neighboring gene solute carrier family 27 (fatty acid transporter), member 1 Neighboring gene 6-phosphogluconolactonase Neighboring gene STARR-positive B cell enhancer ABC_E9025 Neighboring gene collagen beta(1-O)galactosyltransferase 1 Neighboring gene STARR-positive B cell enhancer ABC_E6654 Neighboring gene unc-13 homolog A Neighboring gene predicted gene, 39195

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Distinct roles of BCNP1 in B-cell development and activation. Hong R, et al. Int Immunol, 2020 Jan 9. PMID 31412363
    2. The B cell novel protein 1 (BCNP1) regulates BCR signaling and B cell apoptosis. Hong R, et al. Eur J Immunol, 2019 Jun. PMID 30888050
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1)  1 citation

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein Niban 3
    Names
    BCNP1 homolog
    family with sequence similarity 129, member C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166213.2 → NP_001159685.1  protein Niban 3 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AC162033
      Consensus CDS
      CCDS52587.1
      UniProtKB/TrEMBL
      D3YZB0
      Related
      ENSMUSP00000123432.2, ENSMUST00000143662.8

    2. NM_001384129.1 → NP_001371058.1  protein Niban 3 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform.
      Source sequence(s)
      AC162033

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      72049000..72061599
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509530.4 → XP_006509593.1  protein Niban 3 isoform X1

    2. XM_036153693.1 → XP_036009586.1  protein Niban 3 isoform X2

      UniProtKB/TrEMBL
      Q3TQH6

    RNA

    1. XR_004934733.1 RNA Sequence

    2. XR_379027.4 RNA Sequence

    3. XR_003947209.2 RNA Sequence

    4. XR_379028.4 RNA Sequence

    5. XR_004934734.1 RNA Sequence

    6. XR_004934735.1 RNA Sequence

    7. XR_004934727.1 RNA Sequence

    8. XR_004934728.1 RNA Sequence

    9. XR_004934730.1 RNA Sequence

    10. XR_004934731.1 RNA Sequence

    11. XR_004934732.1 RNA Sequence

    12. XR_004934729.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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