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    LARGE1 LARGE xylosyl- and glucuronyltransferase 1 [ Mirounga leonina (Southern elephant seal) ]

    Gene ID: 117998757, updated on 19-Mar-2024

    Summary

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    Gene symbol
    LARGE1
    Gene description
    LARGE xylosyl- and glucuronyltransferase 1
    See related
    EnsemblRapid:ENSMLOG00005023073
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Mirounga leonina
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Mirounga
    Orthologs
    human mouse all
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    Genomic context

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    See LARGE1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    100 current KU_Mleo_1.0 (GCF_011800145.1) Unplaced Scaffold NW_023270739.1 (10204760..10719206)

    NW_023270739.1Genomic Context describing neighboring genes Neighboring gene intestine specific homeobox Neighboring gene small nucleolar RNA U3 Neighboring gene 60S ribosomal protein L32-like Neighboring gene non-histone chromosomal protein HMG-14-like Neighboring gene cell division cycle-associated protein 3-like Neighboring gene adenylate kinase isoenzyme 6-like Neighboring gene synapsin III Neighboring gene TIMP metallopeptidase inhibitor 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023270739 Unplaced Scaffold Reference KU_Mleo_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables xylosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein O-linked mannosylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LARGE xylosyl- and glucuronyltransferase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Mirounga leonina Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference KU_Mleo_1.0 Primary Assembly

    Genomic

    1. NW_023270739.1 Reference KU_Mleo_1.0 Primary Assembly

      Range
      10204760..10719206
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_034987635.1 → XP_034843526.1  LARGE xylosyl- and glucuronyltransferase 1 isoform X4

      Related
      ENSMLOP00005033569.1, ENSMLOT00005037685.1
      Conserved Domains (2) summary
      cd06431
      Location:138 → 461
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
      pfam13896
      Location:517 → 786
      Glyco_transf_49; Glycosyl-transferase for dystroglycan

    2. XM_034987636.1 → XP_034843527.1  LARGE xylosyl- and glucuronyltransferase 1 isoform X4

      Conserved Domains (2) summary
      cd06431
      Location:138 → 461
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
      pfam13896
      Location:517 → 786
      Glyco_transf_49; Glycosyl-transferase for dystroglycan

    3. XM_034987633.1 → XP_034843524.1  LARGE xylosyl- and glucuronyltransferase 1 isoform X2

      Related
      ENSMLOP00005033608.1, ENSMLOT00005037728.1
      Conserved Domains (2) summary
      cd06431
      Location:238 → 561
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
      pfam13896
      Location:617 → 886
      Glyco_transf_49; Glycosyl-transferase for dystroglycan

    4. XM_034987632.1 → XP_034843523.1  LARGE xylosyl- and glucuronyltransferase 1 isoform X1

      Conserved Domains (2) summary
      cd06431
      Location:201 → 524
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
      pfam13896
      Location:580 → 849
      Glyco_transf_49; Glycosyl-transferase for dystroglycan

    5. XM_034987634.1 → XP_034843525.1  LARGE xylosyl- and glucuronyltransferase 1 isoform X3

      Conserved Domains (2) summary
      cd06431
      Location:201 → 480
      GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
      pfam13896
      Location:536 → 805
      Glyco_transf_49; Glycosyl-transferase for dystroglycan
    Nucleotide Protein
    Heading Accession and Version

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