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    PLCG1 phospholipase C gamma 1 [ Oxyura jamaicensis (ruddy duck) ]

    Gene ID: 118176485, updated on 20-Mar-2024

    Summary

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    Gene symbol
    PLCG1
    Gene description
    phospholipase C gamma 1
    See related
    EnsemblRapid:ENSOJMG00000010024
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oxyura jamaicensis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Anatinae; Oxyura
    Orthologs
    human mouse all
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    Genomic context

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    See PLCG1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    100 current BPBGC_Ojam_1.0 (GCF_011077185.1) 20 NC_048912.1 (2052280..2093506, complement)

    Chromosome 20 - NC_048912.1Genomic Context describing neighboring genes Neighboring gene elastin microfibril interfacer 3 Neighboring gene lipin 3 Neighboring gene zinc fingers and homeoboxes 3 Neighboring gene DNA topoisomerase I Neighboring gene uncharacterized LOC118176912

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_048912.1 Chromosome 20 Reference BPBGC_Ojam_1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol phospholipase C activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phospholipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of epithelial cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Oxyura jamaicensis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference BPBGC_Ojam_1.0

    Genomic

    1. NC_048912.1 Reference BPBGC_Ojam_1.0

      Range
      2052280..2093506 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_035343473.1 → XP_035199364.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X4

      Conserved Domains (10) summary
      smart00149
      Location:944 → 1056
      PLCYc; Phospholipase C, catalytic domain (part); domain Y
      cd00275
      Location:1077 → 1201
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08592
      Location:310 → 457
      PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
      cd09932
      Location:654 → 756
      SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
      cd10341
      Location:536 → 640
      SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
      cd11970
      Location:782 → 841
      SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
      cd13234
      Location:854 → 923
      PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
      cd13362
      Location:24 → 146
      PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
      cd16214
      Location:151 → 297
      EFh_PI-PLCgamma1; EF-hand motif found in phosphoinositide phospholipase C gamma 1 (PI-PLC-gamma1)
      cl17171
      Location:480 → 514
      PH-like; Pleckstrin homology-like domain

    2. XM_035343471.1 → XP_035199362.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X3

      Conserved Domains (10) summary
      smart00149
      Location:944 → 1056
      PLCYc; Phospholipase C, catalytic domain (part); domain Y
      cd00275
      Location:1077 → 1201
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08592
      Location:310 → 457
      PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
      cd09932
      Location:654 → 756
      SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
      cd10341
      Location:536 → 640
      SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
      cd11970
      Location:782 → 841
      SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
      cd13234
      Location:854 → 923
      PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
      cd13362
      Location:24 → 146
      PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
      cd16214
      Location:151 → 297
      EFh_PI-PLCgamma1; EF-hand motif found in phosphoinositide phospholipase C gamma 1 (PI-PLC-gamma1)
      cl17171
      Location:480 → 514
      PH-like; Pleckstrin homology-like domain

    3. XM_035343470.1 → XP_035199361.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2

      Conserved Domains (10) summary
      smart00149
      Location:945 → 1057
      PLCYc; Phospholipase C, catalytic domain (part); domain Y
      cd00275
      Location:1078 → 1202
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08592
      Location:310 → 457
      PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
      cd09932
      Location:654 → 756
      SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
      cd10341
      Location:536 → 640
      SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
      cd11970
      Location:782 → 841
      SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
      cd13234
      Location:855 → 924
      PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
      cd13362
      Location:24 → 146
      PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
      cd16214
      Location:151 → 297
      EFh_PI-PLCgamma1; EF-hand motif found in phosphoinositide phospholipase C gamma 1 (PI-PLC-gamma1)
      cl17171
      Location:480 → 514
      PH-like; Pleckstrin homology-like domain

    4. XM_035343469.1 → XP_035199360.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1

      Related
      ENSOJMP00000016041.1, ENSOJMT00000016573.1
      Conserved Domains (10) summary
      smart00149
      Location:945 → 1057
      PLCYc; Phospholipase C, catalytic domain (part); domain Y
      cd00275
      Location:1078 → 1202
      C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
      cd08592
      Location:310 → 457
      PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
      cd09932
      Location:654 → 756
      SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
      cd10341
      Location:536 → 640
      SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
      cd11970
      Location:782 → 841
      SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
      cd13234
      Location:855 → 924
      PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
      cd13362
      Location:24 → 146
      PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
      cd16214
      Location:151 → 297
      EFh_PI-PLCgamma1; EF-hand motif found in phosphoinositide phospholipase C gamma 1 (PI-PLC-gamma1)
      cl17171
      Location:480 → 514
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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