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    ARHGAP21 Rho GTPase activating protein 21 [ Cygnus atratus (black swan) ]

    Gene ID: 118247353, updated on 20-Mar-2024

    Summary

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    Gene symbol
    ARHGAP21
    Gene description
    Rho GTPase activating protein 21
    See related
    EnsemblRapid:ENSACYG00000013007
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cygnus atratus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Anserinae; Cygnus
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGAP21 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2023_02 current CAtr_DNAZoo_HiC_assembly (GCF_013377495.2) 2 NC_066363.1 (18386164..18510232)
    100 previous assembly Cygnus_atratus_primary_v1.0 (GCF_013377495.1) Unplaced Scaffold NW_023336602.1 (5138266..5261696)

    Chromosome 2 - NC_066363.1Genomic Context describing neighboring genes Neighboring gene threonine synthase like 1 Neighboring gene enkurin, TRPC channel interacting protein Neighboring gene phosphoribosyl transferase domain containing 1 Neighboring gene KIAA1217 ortholog Neighboring gene OTU deubiquitinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Golgi localization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 21

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_013377495.2-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CAtr_DNAZoo_HiC_assembly Primary Assembly

    Genomic

    1. NC_066363.1 Reference CAtr_DNAZoo_HiC_assembly Primary Assembly

      Range
      18386164..18510232
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_050708614.1 → XP_050564571.1  rho GTPase-activating protein 21 isoform X1

    2. XM_035545220.2 → XP_035401113.1  rho GTPase-activating protein 21 isoform X2

      Related
      ENSACYP00000021330.1
      Conserved Domains (3) summary
      cd00992
      Location:53 → 160
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04395
      Location:1109 → 1304
      RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...
      cd01253
      Location:893 → 1001
      PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

    3. XM_035545219.2 → XP_035401112.1  rho GTPase-activating protein 21 isoform X1

      Related
      ENSACYP00000021273.1
      Conserved Domains (3) summary
      cd00992
      Location:53 → 160
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04395
      Location:1162 → 1357
      RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...
      cd01253
      Location:946 → 1054
      PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain
    Nucleotide Protein
    Heading Accession and Version

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