ndufaf4 NADH:ubiquinone oxidoreductase complex assembly factor 4 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ndufaf4provided by ZNC
Official Full Name: NADH:ubiquinone oxidoreductase complex assembly factor 4provided by ZNC
Primary source: ZFIN:ZDB-GENE-060810-114
See related: Ensembl:ENSDARG00000077859 AllianceGenome:ZFIN:ZDB-GENE-060810-114
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7158669; si:ch73-67g20.1
Summary: Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 15. Orthologous to human NDUFAF4 (NADH:ubiquinone oxidoreductase complex assembly factor 4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 20

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (400485..404164)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (411857..415132)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in mitochondrial respiratory chain complex I assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mitochondrial respiratory chain complex I assembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

Names: NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4; NADH dehydrogenase (ubiquinone) complex I, assembly factor 4; UPF0240 protein C6orf66 homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001386274.1 → NP_001373203.1 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

Status: VALIDATED

Source sequence(s)

FP015917

UniProtKB/TrEMBL

A0A8M1RMT7, E7FDX3

Related

ENSDARP00000101916.3, ENSDART00000108872.4

Conserved Domains (1) summary

pfam06784
Location:2 → 172

UPF0240; Uncharacterized protein family (UPF0240)