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    VSIG4 V-set and immunoglobulin domain containing 4 [ Halichoerus grypus (gray seal) ]

    Gene ID: 118528452, updated on 20-Mar-2024

    Summary

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    Gene symbol
    VSIG4
    Gene description
    V-set and immunoglobulin domain containing 4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Halichoerus grypus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Halichoerus
    Orthologs
    human mouse all
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    Genomic context

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    See VSIG4 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    100 current Tufts_HGry_1.1 (GCF_012393455.1) Unplaced Scaffold NW_023402866.1 (16662..71542)

    NW_023402866.1Genomic Context describing neighboring genes Neighboring gene signal peptidase complex subunit 1-like Neighboring gene uncharacterized LOC118528454 Neighboring gene uncharacterized LOC118528453

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023402866 Unplaced Scaffold Reference Tufts_HGry_1.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables complement component C3b binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of T cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of complement activation, alternative pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of interleukin-2 production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of macrophage activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    V-set and immunoglobulin domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Halichoerus grypus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Tufts_HGry_1.1

    Genomic

    1. NW_023402866.1 Reference Tufts_HGry_1.1

      Range
      16662..71542
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036080854.1 → XP_035936747.1  V-set and immunoglobulin domain-containing protein 4 isoform X5

      Conserved Domains (1) summary
      cd16089
      Location:21 → 137
      IgV_CRIg; Immunoglobulin variable (IgV)-like domain in complement receptor of the immunoglobulin superfamily (CRIg)

    2. XM_036080853.1 → XP_035936746.1  V-set and immunoglobulin domain-containing protein 4 isoform X4

      Conserved Domains (2) summary
      cd16082
      Location:146 → 231
      IgC_CRIg; Immunoglobulin (Ig) constant domain of the complement receptor of the immunoglobulin superfamily (CRIg)
      cd16089
      Location:21 → 137
      IgV_CRIg; Immunoglobulin variable (IgV)-like domain in complement receptor of the immunoglobulin superfamily (CRIg)

    3. XM_036080850.1 → XP_035936743.1  V-set and immunoglobulin domain-containing protein 4 isoform X1

      Conserved Domains (2) summary
      cd16082
      Location:146 → 231
      IgC_CRIg; Immunoglobulin (Ig) constant domain of the complement receptor of the immunoglobulin superfamily (CRIg)
      cd16089
      Location:21 → 137
      IgV_CRIg; Immunoglobulin variable (IgV)-like domain in complement receptor of the immunoglobulin superfamily (CRIg)

    4. XM_036080852.1 → XP_035936745.1  V-set and immunoglobulin domain-containing protein 4 isoform X3

      Conserved Domains (2) summary
      cd16082
      Location:146 → 231
      IgC_CRIg; Immunoglobulin (Ig) constant domain of the complement receptor of the immunoglobulin superfamily (CRIg)
      cd16089
      Location:21 → 137
      IgV_CRIg; Immunoglobulin variable (IgV)-like domain in complement receptor of the immunoglobulin superfamily (CRIg)

    5. XM_036080851.1 → XP_035936744.1  V-set and immunoglobulin domain-containing protein 4 isoform X2

      Conserved Domains (2) summary
      cd16082
      Location:146 → 231
      IgC_CRIg; Immunoglobulin (Ig) constant domain of the complement receptor of the immunoglobulin superfamily (CRIg)
      cd16089
      Location:21 → 137
      IgV_CRIg; Immunoglobulin variable (IgV)-like domain in complement receptor of the immunoglobulin superfamily (CRIg)
    Nucleotide Protein
    Heading Accession and Version

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