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    Zfp853 zinc finger protein 853 [ Mus musculus (house mouse) ]

    Gene ID: 330230, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp853provided by MGI
    Official Full Name
    zinc finger protein 853provided by MGI
    Primary source
    MGI:MGI:2685638
    See related
    Ensembl:ENSMUSG00000093910 AllianceGenome:MGI:2685638
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm792
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to human ZNF853 (zinc finger protein 853). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in ovary adult (RPKM 1.8), limb E14.5 (RPKM 1.7) and 16 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp853 in Genome Data Viewer
    Location:
    5 G2; 5 82.06 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (143269283..143279757, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (143285999..143293982, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:143996641-143996853 Neighboring gene zinc finger protein 12 Neighboring gene zinc finger protein 316 Neighboring gene cDNA sequence BC030343 Neighboring gene predicted gene, 52794 Neighboring gene integrator complex subunit 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 853

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001370826.1 → NP_001357755.1  zinc finger protein 853

      Status: VALIDATED

      Source sequence(s)
      AC123686
      Consensus CDS
      CCDS90012.1
      UniProtKB/TrEMBL
      A0A1D5RM95
      Related
      ENSMUSP00000148683.2, ENSMUST00000212355.2
      Conserved Domains (2) summary
      COG5048
      Location:566 → 697
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:597 → 617
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      143269283..143279757 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504776.5 → XP_006504839.1  zinc finger protein 853 isoform X1

      See identical proteins and their annotated locations for XP_006504839.1

      UniProtKB/TrEMBL
      A0A1D5RM95
      Conserved Domains (2) summary
      COG5048
      Location:566 → 697
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:597 → 617
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_036165231.1 → XP_036021124.1  zinc finger protein 853 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:565 → 696
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:596 → 616
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_036165235.1 → XP_036021128.1  zinc finger protein 853 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:418 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_030254608.2 → XP_030110468.1  zinc finger protein 853 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:418 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_030254606.2 → XP_030110466.1  zinc finger protein 853 isoform X3

      UniProtKB/TrEMBL
      A0A1D5RMN1
      Related
      ENSMUSP00000148846.2, ENSMUST00000212715.2
      Conserved Domains (2) summary
      COG5048
      Location:551 → 682
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:582 → 602
      ZF_C2H2; C2H2 Zn finger [structural motif]

    6. XM_030254607.2 → XP_030110467.1  zinc finger protein 853 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:418 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]

    7. XM_030254605.2 → XP_030110465.1  zinc finger protein 853 isoform X3

      UniProtKB/TrEMBL
      A0A1D5RMN1
      Conserved Domains (2) summary
      COG5048
      Location:551 → 682
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:582 → 602
      ZF_C2H2; C2H2 Zn finger [structural motif]

    8. XM_036165232.1 → XP_036021125.1  zinc finger protein 853 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:418 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]

    9. XM_036165233.1 → XP_036021126.1  zinc finger protein 853 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:418 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]

    10. XM_036165234.1 → XP_036021127.1  zinc finger protein 853 isoform X4

      Conserved Domains (2) summary
      COG5048
      Location:418 → 549
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:449 → 469
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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