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    prp45 Prp19 complex subunit Prp45 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2538988, updated on 18-Sep-2024

    Summary

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    Official Symbol
    prp45
    Official Full Name
    Prp19 complex subunit Prp45
    Primary source
    PomBase:SPCC188.11
    Locus tag
    SPOM_SPCC188.11
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    cwf13; snw1; SPCC584.08
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    Genomic context

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    See prp45 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003421.2 (1502643..1504664)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene septin Spn6 Neighboring gene dicer Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The fission yeast ortholog of the coregulator SKIP interacts with the small subunit of U2AF. Ambrozková M, et al. Biochem Biophys Res Commun, 2001 Jun 29. PMID 11414703
    2. Cyclophilins of a novel subfamily interact with SNW/SKIP coregulator in Dictyostelium discoideum and Schizosaccharomyces pombe. Skruzný M, et al. Biochim Biophys Acta, 2001 Oct 31. PMID 11690648
    3. The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast. Aronica L, et al. Nucleic Acids Res, 2016 Feb 29. PMID 26682798, Free PMC Article
    4. Structure of a yeast spliceosome at 3.6-angstrom resolution. Yan C, et al. Science, 2015 Sep 11. PMID 26292707
    5. Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay. Grenier St-Sauveur V, et al. Mol Cell Biol, 2013 Dec. PMID 24081329, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Prp19 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    part_of post-mRNA release spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Prp19 complex subunit Prp45

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1502643..1504664
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023203.3 → NP_588213.1  Prp19 complex subunit Prp45 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588213.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09882
      Conserved Domains (1) summary
      pfam02731
      Location:185 → 338
      SKIP_SNW; SKIP/SNW domain
    Nucleotide Protein
    Heading Accession and Version

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