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    HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 [ Molossus molossus (Pallas's mastiff bat) ]

    Gene ID: 118632795, updated on 30-Mar-2024

    Summary

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    Gene symbol
    HERC4
    Gene description
    HECT and RLD domain containing E3 ubiquitin protein ligase 4
    Locus tag
    HJG59_006245
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Molossus molossus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Molossidae; Molossus
    Orthologs
    human mouse all
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    Genomic context

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    See HERC4 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    100 current mMolMol1.p (GCF_014108415.1) Unplaced Scaffold NW_023425352.1 (49366870..49476624, complement)

    NW_023425352.1Genomic Context describing neighboring genes Neighboring gene MICOS complex subunit MIC19-like Neighboring gene sirtuin 1 Neighboring gene myopalladin Neighboring gene atonal bHLH transcription factor 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023425352 Unplaced Scaffold Reference mMolMol1.p

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    probable E3 ubiquitin-protein ligase HERC4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Molossus molossus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mMolMol1.p

    Genomic

    1. NW_023425352.1 Reference mMolMol1.p

      Range
      49366870..49476624 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036266043.1 → XP_036121936.1  probable E3 ubiquitin-protein ligase HERC4 isoform X8

      UniProtKB/TrEMBL
      A0A7J8DP27
      Conserved Domains (2) summary
      COG5184
      Location:2 → 344
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:701 → 1047
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    2. XM_036266037.1 → XP_036121930.1  probable E3 ubiquitin-protein ligase HERC4 isoform X3

      UniProtKB/TrEMBL
      A0A7J8DP27, A0A7J8DQ10
      Conserved Domains (2) summary
      COG5184
      Location:2 → 374
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:731 → 1077
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    3. XM_036266049.1 → XP_036121942.1  probable E3 ubiquitin-protein ligase HERC4 isoform X14

      UniProtKB/TrEMBL
      A0A7J8DPP2
      Conserved Domains (2) summary
      cd00078
      Location:446 → 792
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam00415
      Location:5 → 53
      RCC1; Regulator of chromosome condensation (RCC1) repeat

    4. XM_036266039.1 → XP_036121932.1  probable E3 ubiquitin-protein ligase HERC4 isoform X5

      UniProtKB/TrEMBL
      A0A7J8DP27, A0A7J8DPC3
      Conserved Domains (2) summary
      COG5184
      Location:2 → 344
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:709 → 1055
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    5. XM_036266044.1 → XP_036121937.1  probable E3 ubiquitin-protein ligase HERC4 isoform X9

      UniProtKB/TrEMBL
      A0A7J8DP27
      Conserved Domains (2) summary
      COG5184
      Location:2 → 374
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:739 → 1013
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    6. XM_036266038.1 → XP_036121931.1  probable E3 ubiquitin-protein ligase HERC4 isoform X4

      UniProtKB/TrEMBL
      A0A7J8DP27
      Conserved Domains (2) summary
      COG5184
      Location:2 → 374
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:739 → 1046
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    7. XM_036266040.1 → XP_036121933.1  probable E3 ubiquitin-protein ligase HERC4 isoform X6

      UniProtKB/TrEMBL
      A0A7J8DP27
      Conserved Domains (2) summary
      COG5184
      Location:2 → 374
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:739 → 1046
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    8. XM_036266036.1 → XP_036121929.1  probable E3 ubiquitin-protein ligase HERC4 isoform X2

      UniProtKB/TrEMBL
      A0A7J8DP27
      Conserved Domains (2) summary
      COG5184
      Location:2 → 368
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:733 → 1079
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    9. XM_036266041.1 → XP_036121934.1  probable E3 ubiquitin-protein ligase HERC4 isoform X7

      UniProtKB/TrEMBL
      A0A7J8DP27
      Conserved Domains (2) summary
      COG5184
      Location:2 → 374
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:739 → 1052
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    10. XM_036266035.1 → XP_036121928.1  probable E3 ubiquitin-protein ligase HERC4 isoform X1

      UniProtKB/TrEMBL
      A0A7J8DP27
      Conserved Domains (2) summary
      COG5184
      Location:2 → 374
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:739 → 1085
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    11. XM_036266045.1 → XP_036121938.1  probable E3 ubiquitin-protein ligase HERC4 isoform X10

      UniProtKB/TrEMBL
      A0A7J8DPA8
      Conserved Domains (2) summary
      COG5184
      Location:12 → 298
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cd00078
      Location:669 → 1015
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    12. XM_036266048.1 → XP_036121941.1  probable E3 ubiquitin-protein ligase HERC4 isoform X13

      UniProtKB/TrEMBL
      A0A7J8DPP2
      Conserved Domains (2) summary
      cd00078
      Location:454 → 800
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
      pfam00415
      Location:5 → 53
      RCC1; Regulator of chromosome condensation (RCC1) repeat

    13. XM_036266046.1 → XP_036121939.1  probable E3 ubiquitin-protein ligase HERC4 isoform X11

      UniProtKB/TrEMBL
      A0A7J8DP27
      Conserved Domains (2) summary
      COG5184
      Location:2 → 374
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cl27008
      Location:739 → 924
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    14. XM_036266047.1 → XP_036121940.1  probable E3 ubiquitin-protein ligase HERC4 isoform X12

      UniProtKB/TrEMBL
      A0A7J8DP27
      Conserved Domains (2) summary
      COG5184
      Location:2 → 344
      ATS1; Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
      cl27008
      Location:709 → 843
      HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...

    RNA

    1. XR_004960062.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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