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    cph1 Clr6 histone deacetylase-associated PHD protein-1 Cph1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542318, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cph1
    Official Full Name
    Clr6 histone deacetylase-associated PHD protein-1 Cph1
    Primary source
    PomBase:SPAC16C9.05
    Locus tag
    SPOM_SPAC16C9.05
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See cph1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (799367..800981)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene CCR4-Not complex subunit Mot2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ATP-dependent RNA helicase Upf1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cdk9 and H2Bub1 signal to Clr6-CII/Rpd3S to suppress aberrant antisense transcription. Sansó M, et al. Nucleic Acids Res, 2020 Jul 27. PMID 32496538, Free PMC Article
    2. Class I histone deacetylase complex: Structure and functional correlates. Wang X, et al. Proc Natl Acad Sci U S A, 2023 Jul 25. PMID 37459529, Free PMC Article
    3. Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection. Nicolas E, et al. Nat Struct Mol Biol, 2007 May. PMID 17450151
    4. Two assembly modes for SIN3 histone deacetylase complexes. Wang C, et al. Cell Discov, 2023 Apr 19. PMID 37076472, Free PMC Article
    5. Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment. Shevchenko A, et al. Genome Biol, 2008. PMID 19040720, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of Rpd3S complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Rpd3S complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Clr6 histone deacetylase-associated PHD protein-1 Cph1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      799367..800981
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018476.3 → NP_593079.1  Clr6 histone deacetylase-associated PHD protein-1 Cph1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593079.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09819
      Conserved Domains (1) summary
      cd15535
      Location:119 → 163
      PHD1_Rco1; PHD finger 1 found in Saccharomyces cerevisiae transcriptional regulatory protein Rco1 and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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