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    crn1 coronin Crn1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541961, updated on 18-Sep-2024

    Summary

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    Official Symbol
    crn1
    Official Full Name
    coronin Crn1
    Primary source
    PomBase:SPAC23C4.02
    Locus tag
    SPOM_SPAC23C4.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See crn1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003424.3 (1032105..1034167)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene succinate-semialdehyde dehydrogenase Neighboring gene ncRNA Neighboring gene histone acetyltransferase Hat1 Neighboring gene ncRNA Neighboring gene haspin-like kinase Hrk1 Neighboring gene ncRNA Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of actin polymerization and actin cables in actin-patch movement in Schizosaccharomyces pombe. Pelham RJ Jr, et al. Nat Cell Biol, 2001 Mar. PMID 11231572
    2. Characterization of dip1p reveals a switch in Arp2/3-dependent actin assembly for fission yeast endocytosis. Basu R, et al. Curr Biol, 2011 Jun 7. PMID 21620704, Free PMC Article
    3. Aip1 promotes actin filament severing by cofilin and regulates constriction of the cytokinetic contractile ring. Chen Q, et al. J Biol Chem, 2015 Jan 23. PMID 25451933, Free PMC Article
    4. Reorganization of the growth pattern of Schizosaccharomyces pombe in invasive filament formation. Dodgson J, et al. Eukaryot Cell, 2010 Nov. PMID 20870879, Free PMC Article
    5. Quantitative analysis of the mechanism of endocytic actin patch assembly and disassembly in fission yeast. Sirotkin V, et al. Mol Biol Cell, 2010 Aug 15. PMID 20587778, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin filament bundle assembly NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in actin filament polymerization NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actin cortical patch IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in endocytic vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mating projection actin fusion focus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitotic actomyosin contractile ring IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    coronin Crn1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1032105..1034167
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018571.3 → NP_593175.1  coronin Crn1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593175.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13923
      Conserved Domains (4) summary
      pfam08953
      Location:7 → 64
      DUF1899; Domain of unknown function (DUF1899)
      pfam16300
      Location:345 → 387
      WD40_4; Type of WD40 repeat
      sd00039
      Location:85 → 132
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:77 → 324
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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