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    elf1 AAA family ATPase Elf1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543082, updated on 18-Sep-2024

    Summary

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    Official Symbol
    elf1
    Official Full Name
    AAA family ATPase Elf1
    Primary source
    PomBase:SPAC3C7.08c
    Locus tag
    SPOM_SPAC3C7.08C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See elf1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (2079070..2082517, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene serine/threonine protein kinase Pit1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene arginine-tRNA--protein transferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene lysine methyltransferase Set8 Neighboring gene peroxin 13 Neighboring gene calnexin Cnx1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Loss of Elongation-Like Factor 1 Spontaneously Induces Diverse, RNase H-Related Suppressor Mutations in Schizosaccharomyces pombe. Marayati BF, et al. Genetics, 2018 Aug. PMID 29844133, Free PMC Article
    2. The fission yeast homologue of Glel is essential for growth and involved in mRNA export. Moon D, et al. J Microbiol, 2008 Aug. PMID 18758733
    3. Elf1p, a member of the ABC class of ATPases, functions as a mRNA export factor in Schizosacchromyces pombe. Kozak L, et al. J Biol Chem, 2002 Sep 13. PMID 12110682
    4. Homolog of BRCA2-interacting Dss1p and Uap56p link Mlo3p and Rae1p for mRNA export in fission yeast. Thakurta AG, et al. EMBO J, 2005 Jul 20. PMID 15990877, Free PMC Article
    5. Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site. Roberts-Galbraith RH, et al. Mol Cell, 2010 Jul 9. PMID 20603077, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Results provide evidence that the loss of ELF1 spontaneously induces diverse, RNase H-related suppressor mutations in Schizosaccharomyces pombe.
      Title: Loss of Elongation-Like Factor 1 Spontaneously Induces Diverse, RNase H-Related Suppressor Mutations in Schizosaccharomyces pombe.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in poly(A)+ mRNA export from nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    AAA family ATPase Elf1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2079070..2082517 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019040.3 → NP_593609.1  AAA family ATPase Elf1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593609.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14134
      Conserved Domains (5) summary
      cd03221
      Location:445 → 635
      ABCF_EF-3; ATP-binding cassette domain of elongation factor 3, subfamily F
      COG0488
      Location:445 → 981
      Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]
      cd00020
      Location:137 → 231
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      sd00044
      Location:99 → 126
      HEAT; HEAT repeat [structural motif]
      cl21455
      Location:696 → 984
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version

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