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    mms19 TFIIH regulator Mms19 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541536, updated on 14-Nov-2024

    Summary

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    Official Symbol
    mms19
    Official Full Name
    TFIIH regulator Mms19
    Primary source
    PomBase:SPAC1071.02
    Locus tag
    SPOM_SPAC1071.02
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See mms19 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003424.3 (3858218..3861822)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene cleavage and polyadenylation specificity factor complex subunit Pta1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein Sil1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene signal peptidase subunit Spc2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Coordination of DNA replication and histone modification by the Rik1-Dos2 complex. Li F, et al. Nature, 2011 Jul 3. PMID 21725325, Free PMC Article
    2. Conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing. Chalamcharla VR, et al. Proc Natl Acad Sci U S A, 2015 Dec 22. PMID 26631744, Free PMC Article
    3. CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation. Vanoosthuyse V, et al. PLoS Genet, 2014 Jun. PMID 24945319, Free PMC Article
    4. Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. Wiley DJ, et al. Front Physiol, 2020. PMID 32435206, Free PMC Article
    5. Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries. Wang J, et al. Genes Dev, 2013 Sep 1. PMID 24013502, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity NAS
    Non-traceable Author Statement
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein maturation by iron-sulfur cluster transfer IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    part_of cytosolic [4Fe-4S] assembly targeting complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in pericentric heterochromatin EXP
    Inferred from Experiment
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TFIIH regulator Mms19

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      3858218..3861822
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019773.3 → NP_594352.1  TFIIH regulator Mms19 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594352.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9UTR1
      Conserved Domains (2) summary
      pfam12460
      Location:528 → 953
      MMS19_C; RNAPII transcription regulator C-terminal
      pfam14500
      Location:46 → 304
      MMS19_N; Dos2-interacting transcription regulator of RNA-Pol-II
    Nucleotide Protein
    Heading Accession and Version

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