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    hyfF hydrogenase 4 component F [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946962, updated on 3-Dec-2024

    Summary

    Official Symbol
    hyfF
    Official Full Name
    hydrogenase 4 component F
    Primary source
    ECOCYC:G7303
    Locus tag
    b2486
    See related
    ASAP:ABE-0008191
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2482
    Summary
    On the basis of sequence similarity to hycBCDEFG, which encodes hydrogenase 3, the ten-gene cluster hyfABCDEFGHIJ was presumed to encode a hydrogenase that interacts with formate dehydrogenase (FdhF) to produce an active formate hydrogenlyase complex. [More information is available at EcoCyc: G7303].
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    Genomic context

    Sequence:
    NC_000913.3 (2606917..2608497)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene hydrogenase 4 component D Neighboring gene hydrogenase 4 component E Neighboring gene hydrogenase 4 catalytic subunit HyfG Neighboring gene hydrogenase 4 component H Neighboring gene hydrogenase 4 catalytic subunit HyfI Neighboring gene putative hydrogenase 4 assembly protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in anaerobic electron transport chain NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in anaerobic respiration NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in formate oxidation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in glucose catabolic process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of [Ni-Fe] hydrogenase complex RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    part_of formate dehydrogenase complex NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2606917..2608497
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416981.1 hydrogenase 4 component F [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416981.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A7T2J2U5
      Conserved Domains (1) summary
      PRK06458
      Location:1495
      PRK06458; hydrogenase 4 subunit F; Validated