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    ppx exopolyphosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946970, updated on 17-Dec-2024

    Summary

    Official Symbol
    ppx
    Official Full Name
    exopolyphosphatase
    Primary source
    ECOCYC:EG11403
    Locus tag
    b2502
    See related
    ASAP:ABE-0008238
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2498
    Summary
    PDB structure from O157:H7 has identical sequence as K-12. [More information is available at EcoGene: EG11403]. Exopolyphosphatase (PPX) degrades inorganic polyphosphates (polyP). [More information is available at EcoCyc: EG11403].
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    Genomic context

    Sequence:
    NC_000913.3 (2625115..2626656)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene phosphoribosylformylglycinamide cyclo-ligase Neighboring gene phosphoribosylglycinamide formyltransferase 1 Neighboring gene polyphosphate kinase Neighboring gene cyclic di-GMP phosphodiesterase PdeF Neighboring gene nickel/cobalt stress response protein YfgG

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables exopolyphosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables exopolyphosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables exopolyphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables guanosine tetraphosphate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in phosphorus metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in polyphosphate catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within polyphosphate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    exopolyphosphatase
    NP_416997.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2625115..2626656
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416997.1 exopolyphosphatase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416997.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9ATD1, A0A8S7F3A2
      Conserved Domains (1) summary
      PRK10854
      Location:1513
      PRK10854; exopolyphosphatase; Provisional