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    NSD3 nuclear receptor binding SET domain protein 3 [ Falco rusticolus (gyrfalcon) ]

    Gene ID: 119140423, updated on 3-Aug-2024

    Summary

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    Gene symbol
    NSD3
    Gene description
    nuclear receptor binding SET domain protein 3
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Falco rusticolus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Falconiformes; Falconidae; Falco
    Orthologs
    human mouse all
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    Genomic context

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    See NSD3 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    100 current bFalRus1.pri (GCF_015220075.1) 20 NC_051206.1 (5423867..5476363, complement)

    Chromosome 20 - NC_051206.1Genomic Context describing neighboring genes Neighboring gene DDHD domain containing 2 Neighboring gene phospholipid phosphatase 5 Neighboring gene leucine zipper and EF-hand containing transmembrane protein 2 Neighboring gene fibroblast growth factor receptor 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_051206.1 Chromosome 20 Reference bFalRus1.pri Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone H3K36 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone-lysine N-methyltransferase NSD3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Falco rusticolus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bFalRus1.pri Primary Assembly

    Genomic

    1. NC_051206.1 Reference bFalRus1.pri Primary Assembly

      Range
      5423867..5476363 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_037371767.1 → XP_037227664.1  histone-lysine N-methyltransferase NSD3 isoform X1

      Conserved Domains (12) summary
      cd05837
      Location:267 → 384
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      cd05838
      Location:956 → 1049
      WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
      COG5034
      Location:610 → 743
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      COG5180
      Location:370 → 566
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd15649
      Location:700 → 743
      PHD1_NSD3; PHD finger 1 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15652
      Location:748 → 794
      PHD2_NSD3; PHD finger 2 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15655
      Location:795 → 847
      PHD3_NSD3; PHD finger 3 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15658
      Location:915 → 950
      PHD4_NSD3; PHD finger 4 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15661
      Location:1321 → 1363
      PHD5_NSD3; PHD finger 5 found in nuclear SET domain-containing protein 3 (NSD3)
      cd19212
      Location:1142 → 1283
      SET_NSD3; SET domain (including post-SET domain) found in nuclear receptor-binding SET domain-containing protein 3 (NSD3) and similar proteins
      pfam17907
      Location:1102 → 1140
      AWS; AWS domain
      pfam17982
      Location:1362 → 1411
      C5HCH; NSD Cys-His rich domain

    2. XM_037371766.1 → XP_037227663.1  histone-lysine N-methyltransferase NSD3 isoform X1

      Conserved Domains (12) summary
      cd05837
      Location:267 → 384
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      cd05838
      Location:956 → 1049
      WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
      COG5034
      Location:610 → 743
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      COG5180
      Location:370 → 566
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd15649
      Location:700 → 743
      PHD1_NSD3; PHD finger 1 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15652
      Location:748 → 794
      PHD2_NSD3; PHD finger 2 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15655
      Location:795 → 847
      PHD3_NSD3; PHD finger 3 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15658
      Location:915 → 950
      PHD4_NSD3; PHD finger 4 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15661
      Location:1321 → 1363
      PHD5_NSD3; PHD finger 5 found in nuclear SET domain-containing protein 3 (NSD3)
      cd19212
      Location:1142 → 1283
      SET_NSD3; SET domain (including post-SET domain) found in nuclear receptor-binding SET domain-containing protein 3 (NSD3) and similar proteins
      pfam17907
      Location:1102 → 1140
      AWS; AWS domain
      pfam17982
      Location:1362 → 1411
      C5HCH; NSD Cys-His rich domain

    3. XM_037371764.1 → XP_037227661.1  histone-lysine N-methyltransferase NSD3 isoform X1

      Conserved Domains (12) summary
      cd05837
      Location:267 → 384
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      cd05838
      Location:956 → 1049
      WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
      COG5034
      Location:610 → 743
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      COG5180
      Location:370 → 566
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd15649
      Location:700 → 743
      PHD1_NSD3; PHD finger 1 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15652
      Location:748 → 794
      PHD2_NSD3; PHD finger 2 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15655
      Location:795 → 847
      PHD3_NSD3; PHD finger 3 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15658
      Location:915 → 950
      PHD4_NSD3; PHD finger 4 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15661
      Location:1321 → 1363
      PHD5_NSD3; PHD finger 5 found in nuclear SET domain-containing protein 3 (NSD3)
      cd19212
      Location:1142 → 1283
      SET_NSD3; SET domain (including post-SET domain) found in nuclear receptor-binding SET domain-containing protein 3 (NSD3) and similar proteins
      pfam17907
      Location:1102 → 1140
      AWS; AWS domain
      pfam17982
      Location:1362 → 1411
      C5HCH; NSD Cys-His rich domain

    4. XM_037371769.1 → XP_037227666.1  histone-lysine N-methyltransferase NSD3 isoform X2

      Conserved Domains (12) summary
      cd05837
      Location:267 → 384
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      cd05838
      Location:906 → 999
      WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
      COG5034
      Location:610 → 743
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      COG5180
      Location:370 → 566
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd15649
      Location:700 → 743
      PHD1_NSD3; PHD finger 1 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15652
      Location:748 → 794
      PHD2_NSD3; PHD finger 2 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15655
      Location:795 → 847
      PHD3_NSD3; PHD finger 3 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15658
      Location:861 → 900
      PHD4_NSD3; PHD finger 4 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15661
      Location:1271 → 1313
      PHD5_NSD3; PHD finger 5 found in nuclear SET domain-containing protein 3 (NSD3)
      cd19212
      Location:1092 → 1233
      SET_NSD3; SET domain (including post-SET domain) found in nuclear receptor-binding SET domain-containing protein 3 (NSD3) and similar proteins
      pfam17907
      Location:1052 → 1090
      AWS; AWS domain
      pfam17982
      Location:1312 → 1361
      C5HCH; NSD Cys-His rich domain

    5. XM_037371765.1 → XP_037227662.1  histone-lysine N-methyltransferase NSD3 isoform X1

      Conserved Domains (12) summary
      cd05837
      Location:267 → 384
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      cd05838
      Location:956 → 1049
      WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
      COG5034
      Location:610 → 743
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      COG5180
      Location:370 → 566
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd15649
      Location:700 → 743
      PHD1_NSD3; PHD finger 1 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15652
      Location:748 → 794
      PHD2_NSD3; PHD finger 2 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15655
      Location:795 → 847
      PHD3_NSD3; PHD finger 3 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15658
      Location:915 → 950
      PHD4_NSD3; PHD finger 4 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15661
      Location:1321 → 1363
      PHD5_NSD3; PHD finger 5 found in nuclear SET domain-containing protein 3 (NSD3)
      cd19212
      Location:1142 → 1283
      SET_NSD3; SET domain (including post-SET domain) found in nuclear receptor-binding SET domain-containing protein 3 (NSD3) and similar proteins
      pfam17907
      Location:1102 → 1140
      AWS; AWS domain
      pfam17982
      Location:1362 → 1411
      C5HCH; NSD Cys-His rich domain

    6. XM_037371770.1 → XP_037227667.1  histone-lysine N-methyltransferase NSD3 isoform X3

      Conserved Domains (8) summary
      cd05837
      Location:267 → 384
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      COG5034
      Location:610 → 743
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      COG5180
      Location:370 → 562
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd15649
      Location:700 → 743
      PHD1_NSD3; PHD finger 1 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15652
      Location:748 → 794
      PHD2_NSD3; PHD finger 2 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15655
      Location:795 → 847
      PHD3_NSD3; PHD finger 3 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15658
      Location:915 → 950
      PHD4_NSD3; PHD finger 4 found in nuclear SET domain-containing protein 3 (NSD3)
      cl02554
      Location:956 → 981
      PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...

    7. XM_037371771.1 → XP_037227668.1  histone-lysine N-methyltransferase NSD3 isoform X4

      Conserved Domains (6) summary
      cd05837
      Location:267 → 384
      MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
      COG5034
      Location:610 → 743
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      COG5180
      Location:370 → 562
      PBP1; PAB1-binding protein PBP1, interacts with poly(A)-binding protein [RNA processing and modification]
      cd15649
      Location:700 → 743
      PHD1_NSD3; PHD finger 1 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15652
      Location:748 → 794
      PHD2_NSD3; PHD finger 2 found in nuclear SET domain-containing protein 3 (NSD3)
      cd15655
      Location:795 → 847
      PHD3_NSD3; PHD finger 3 found in nuclear SET domain-containing protein 3 (NSD3)
    Nucleotide Protein
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