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    R04A9.7 Non-specific serine/threonine protein kinase [ Caenorhabditis elegans ]

    Gene ID: 3565956, updated on 4-Jan-2025

    Summary

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    Official Symbol
    R04A9.7
    Official Full Name
    Non-specific serine/threonine protein kinase
    Primary source
    WormBase:WBGene00044281
    Locus tag
    CELE_R04A9.7
    See related
    AllianceGenome:WB:WBGene00044281
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in TORC1 signaling. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human RPS6KB1 (ribosomal protein S6 kinase B1). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See R04A9.7 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    4
    Sequence:
    Chromosome: X; NC_003284.9 (391360..394892, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Homeobox domain-containing protein Neighboring gene NR LBD domain-containing protein Neighboring gene F-box domain-containing protein Neighboring gene Late nodulin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in TORC1 signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Non-specific serine/threonine protein kinase
    NP_001024829.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      391360..394892 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001029658.8 → NP_001024829.2  Non-specific serine/threonine protein kinase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024829.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21694
      Conserved Domains (2) summary
      smart00220
      Location:49 → 305
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:52 → 368
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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