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    MetRS methionyl-tRNA synthetase 1 [ Drosophila ananassae ]

    Gene ID: 6496582, updated on 22-May-2024

    Summary

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    Gene symbol
    MetRS
    Gene description
    methionyl-tRNA synthetase 1
    Locus tag
    Dana_GF13746
    See related
    EnsemblRapid:LOC6496582
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Drosophila ananassae
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    GF13746; GF13746-PA
    Orthologs
    fruit fly all
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    Genomic context

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    See MetRS in Genome Data Viewer
    Location:
    chromosome: 3L
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    102 current ASM1763931v2 (GCF_017639315.1) 3L NC_057929.1 (17797369..17801132)
    101 previous assembly DanaRS2.1 (GCF_003285975.2) Unplaced Scaffold NW_022473265.1 (74132..77893, complement)

    Chromosome 3L - NC_057929.1Genomic Context describing neighboring genes Neighboring gene Juvenile hormone epoxide hydrolase 1 Neighboring gene microtubule-associated protein RP/EB family member 3 Neighboring gene coiled-coil domain-containing protein 130 homolog Neighboring gene protein dopey-1 homolog Neighboring gene uncharacterized LOC6493986 Neighboring gene uncharacterized LOC26514470

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolution of genes and genomes on the Drosophila phylogeny. Drosophila 12 Genomes Consortium, et al. Nature, 2007 Nov 8. PMID 17994087
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables methionine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in methionyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of aminoacyl-tRNA synthetase multienzyme complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    methionine--tRNA ligase, cytoplasmic
    Names
    Dana\GF13746
    Dana\GF13746-PA
    dana_GLEANR_13753

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Drosophila ananassae Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1763931v2

    Genomic

    1. NC_057929.1 Reference ASM1763931v2

      Range
      17797369..17801132
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001961160.4 → XP_001961196.1  methionine--tRNA ligase, cytoplasmic

      See identical proteins and their annotated locations for XP_001961196.1

      UniProtKB/TrEMBL
      B3MI08
      Related
      XP_001961196.1, XM_001961160.4
      Conserved Domains (7) summary
      cd07957
      Location:634 → 763
      Anticodon_Ia_Met; Anticodon-binding domain of methionyl tRNA synthetases
      cd00814
      Location:255 → 625
      MetRS_core; catalytic core domain of methioninyl-tRNA synthetases
      COG0625
      Location:1 → 170
      GstA; Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]
      PRK12268
      Location:254 → 812
      PRK12268; methionyl-tRNA synthetase; Reviewed
      cd00570
      Location:1 → 65
      GST_N_family; Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic ...
      cd00939
      Location:828 → 871
      MetRS_RNA; MetRS_RNA binding domain. This short RNA-binding domain is found at the C-terminus of MetRS in several higher eukaryote aminoacyl-tRNA synthetases (aaRSs). It is repeated in Drosophila MetRS. This domain consists of a helix-turn-helix structure, which is ...
      cl02776
      Location:63 → 164
      GST_C_family; C-terminal, alpha helical domain of the Glutathione S-transferase family
    Nucleotide Protein Strain
    Heading Accession and Version

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