U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    Lilrb1 leukocyte immunoglobulin like receptor B1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100912456, updated on 4-Jan-2025

    Summary

    Go to the top of the page Help
    Symbol
    Lilrb1provided by RGD
    Full Name
    leukocyte immunoglobulin like receptor B1provided by RGD
    Primary source
    RGD:6487069
    See related
    AllianceGenome:RGD:6487069
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable inhibitory MHC class I receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and immune response-regulating signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Spleen (RPKM 54.7), Lung (RPKM 34.9) and 9 other tissues See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Lilrb1 in Genome Data Viewer
    Location:
    1q12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (74372772..74379871)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (65457264..65464523)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (63883684..63891697)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene paired-Ig-like receptor A2 Neighboring gene small nuclear ribonucleoprotein polypeptide C, pseudogene 4 Neighboring gene constitutive coactivator of PPAR-gamma-like protein 1 Neighboring gene paired Ig-like receptor B Neighboring gene ribosomal protein S9 Neighboring gene tRNA splicing endonuclease subunit 34

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables inhibitory MHC class I receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cytokine-mediated signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in immune response-regulating signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    leukocyte immunoglobulin like receptor B1; leukocyte immunoglobulin-like receptor subfamily B member 3-like
    Names
    leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      74372772..74379871
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006228040.5 → XP_006228102.1  leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X3

      See identical proteins and their annotated locations for XP_006228102.1

      Conserved Domains (2) summary
      smart00410
      Location:530 → 617
      IG_like; Immunoglobulin like
      cl11960
      Location:225 → 315
      Ig; Immunoglobulin domain

    2. XM_003748711.6 → XP_003748759.1  leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X1

      See identical proteins and their annotated locations for XP_003748759.1

      UniProtKB/TrEMBL
      A0A0G2JYU1
      Conserved Domains (2) summary
      smart00410
      Location:530 → 617
      IG_like; Immunoglobulin like
      cl11960
      Location:225 → 315
      Ig; Immunoglobulin domain

    3. XM_006228039.5 → XP_006228101.1  leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X2

      See identical proteins and their annotated locations for XP_006228101.1

      UniProtKB/TrEMBL
      A0A0G2KAU3, A0A8I6AZE5
      Conserved Domains (2) summary
      smart00410
      Location:530 → 617
      IG_like; Immunoglobulin like
      cl11960
      Location:225 → 315
      Ig; Immunoglobulin domain

    4. XM_006228042.5 → XP_006228104.1  leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X4

      See identical proteins and their annotated locations for XP_006228104.1

      Conserved Domains (2) summary
      smart00410
      Location:465 → 552
      IG_like; Immunoglobulin like
      cl11960
      Location:160 → 250
      Ig; Immunoglobulin domain

    5. XM_039100379.2 → XP_038956307.1  leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X6

      Conserved Domains (3) summary
      cd00096
      Location:331 → 334
      Ig; Ig strand A' [structural motif]
      cd16843
      Location:225 → 314
      IgC2_D1_D2_LILR_KIR_like; Immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors, Natural killer inhibitory receptors (KIRs) and similar domains; member of Immunoglobulin Constant-2 set of IgSF domains
      cl11960
      Location:325 → 417
      Ig; Immunoglobulin domain

    6. XM_063280906.1 → XP_063136976.1  leukocyte immunoglobulin-like receptor subfamily B member 3-like isoform X5

    RNA

    1. XR_010062963.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.