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    Zfp628 zinc finger protein 628 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100359484, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp628provided by RGD
    Official Full Name
    zinc finger protein 628provided by RGD
    Primary source
    RGD:2323809
    See related
    EnsemblRapid:ENSRNOG00000038622 AllianceGenome:RGD:2323809
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in spermatogenesis. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human ZNF628 (zinc finger protein 628). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 13.7), Kidney (RPKM 12.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp628 in Genome Data Viewer
    Location:
    1q12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (77942431..77950013, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (68913600..68921186, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (72465403..72474442, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene scavenger receptor cysteine rich family member with 5 domains Neighboring gene N-acetyltransferase 14 Neighboring gene similar to human chromosome 19 open reading frame 85 Neighboring gene isochorismatase domain containing 2A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. ZEC, a zinc finger protein with novel binding specificity and transcription regulatory activity. Chen GY, et al. Gene, 2004 Sep 29. PMID 15556296
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables DNA-binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 628

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001401702.1 → NP_001388631.1  zinc finger protein 628

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      D3ZI74
      Related
      ENSRNOP00000030688.7, ENSRNOT00000029136.7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      77942431..77950013 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039100601.2 → XP_038956529.1  zinc finger protein 628 isoform X3

      UniProtKB/TrEMBL
      D4A8F7
      Conserved Domains (3) summary
      COG5048
      Location:364 → 553
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:66 → 86
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:272 → 289
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_006228303.5 → XP_006228365.1  zinc finger protein 628 isoform X1

      See identical proteins and their annotated locations for XP_006228365.1

      UniProtKB/TrEMBL
      D3ZI74
      Conserved Domains (5) summary
      COG5048
      Location:23 → 221
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:148 → 168
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:354 → 371
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:615 → 637
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:573 → 598
      zf-H2C2_2; Zinc-finger double domain

    3. XM_039100598.2 → XP_038956526.1  zinc finger protein 628 isoform X3

      UniProtKB/TrEMBL
      D4A8F7
      Conserved Domains (3) summary
      COG5048
      Location:364 → 553
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:66 → 86
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:272 → 289
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_039100593.2 → XP_038956521.1  zinc finger protein 628 isoform X2

      Related
      ENSRNOP00000104000.1, ENSRNOT00000136986.1
      Conserved Domains (3) summary
      COG5048
      Location:60 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:468 → 488
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:289 → 306
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_008759016.4 → XP_008757238.1  zinc finger protein 628 isoform X1

      See identical proteins and their annotated locations for XP_008757238.1

      UniProtKB/TrEMBL
      D3ZI74
      Related
      ENSRNOP00000082027.1, ENSRNOT00000116046.2
      Conserved Domains (5) summary
      COG5048
      Location:23 → 221
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:148 → 168
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:354 → 371
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:615 → 637
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:573 → 598
      zf-H2C2_2; Zinc-finger double domain

    6. XM_063280976.1 → XP_063137046.1  zinc finger protein 628 isoform X1

      UniProtKB/TrEMBL
      D3ZI74

    7. XM_063281063.1 → XP_063137133.1  zinc finger protein 628 isoform X3

      UniProtKB/TrEMBL
      D4A8F7

    8. XM_063280967.1 → XP_063137037.1  zinc finger protein 628 isoform X1

      UniProtKB/TrEMBL
      D3ZI74
      Related
      ENSRNOP00000107204.1, ENSRNOT00000162199.1

    9. XM_039100605.2 → XP_038956533.1  zinc finger protein 628 isoform X3

      UniProtKB/TrEMBL
      D4A8F7
      Conserved Domains (3) summary
      COG5048
      Location:364 → 553
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:66 → 86
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:272 → 289
      ZF_C2H2; C2H2 Zn finger [structural motif]

    10. XM_017589974.3 → XP_017445463.1  zinc finger protein 628 isoform X1

      UniProtKB/TrEMBL
      D3ZI74
      Conserved Domains (5) summary
      COG5048
      Location:23 → 221
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:148 → 168
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:354 → 371
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:615 → 637
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:573 → 598
      zf-H2C2_2; Zinc-finger double domain

    11. XM_063281027.1 → XP_063137097.1  zinc finger protein 628 isoform X1

      UniProtKB/TrEMBL
      D3ZI74

    12. XM_063281034.1 → XP_063137104.1  zinc finger protein 628 isoform X1

      UniProtKB/TrEMBL
      D3ZI74
    Nucleotide Protein Strain
    Heading Accession and Version

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