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    Albfm1 albumin superfamily member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360919, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Albfm1provided by RGD
    Official Full Name
    albumin superfamily member 1provided by RGD
    Primary source
    RGD:1561929
    See related
    EnsemblRapid:ENSRNOG00000039504 AllianceGenome:RGD:1561929
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Arg
    Summary
    Predicted to be located in extracellular space. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 320.2) and Kidney (RPKM 197.8) See more
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    Genomic context

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    See Albfm1 in Genome Data Viewer
    Location:
    14p22
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (17762615..17814075, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (17478159..17525047, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (19028810..19072734, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene Ras association domain family member 6 Neighboring gene uncharacterized LOC120096582 Neighboring gene uncharacterized LOC134481727 Neighboring gene afamin Neighboring gene uncharacterized LOC134481728

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Alpha-fetoprotein related gene (ARG): a new member of the albumin gene family that is no longer functional in primates. Naidu S, et al. Gene, 2010 Jan 1. PMID 19733224, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    alpha-fetoprotein related protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108356.2 → NP_001101826.2  alpha-fetoprotein related protein

      Status: VALIDATED

      Source sequence(s)
      FQ092274, JAXUCZ010000014
      UniProtKB/TrEMBL
      A0A8I6AB30, F7FAY5
      Related
      ENSRNOP00000057287.2, ENSRNOT00000060548.5
      Conserved Domains (1) summary
      pfam00273
      Location:225 → 396
      Serum_albumin; Serum albumin family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      17762615..17814075 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006250759.5 → XP_006250821.1  alpha-fetoprotein related protein isoform X1

      See identical proteins and their annotated locations for XP_006250821.1

      UniProtKB/TrEMBL
      A0A8I6AB30
      Conserved Domains (1) summary
      pfam00273
      Location:207 → 378
      Serum_albumin; Serum albumin family

    2. XM_063273336.1 → XP_063129406.1  alpha-fetoprotein related protein isoform X3

      UniProtKB/TrEMBL
      A0A8I6AB30

    3. XM_039092166.2 → XP_038948094.1  alpha-fetoprotein related protein isoform X4

      UniProtKB/TrEMBL
      A0A8I6AB30
      Conserved Domains (2) summary
      pfam00273
      Location:132 → 303
      Serum_albumin; Serum albumin family
      cl00031
      Location:1 → 112
      ALBUMIN; Albumin domain, contains five or six internal disulphide bonds; albuminoid superfamily includes alpha-fetoprotein which binds various cations, fatty acids and bilirubin; vitamin D-binding protein which binds to vitamin D, its metabolites, and fatty acids; ...

    4. XM_063273335.1 → XP_063129405.1  alpha-fetoprotein related protein isoform X2

      UniProtKB/TrEMBL
      A0A8I6AB30

    5. XM_039092167.2 → XP_038948095.1  alpha-fetoprotein related protein isoform X5

      UniProtKB/TrEMBL
      Q5M885
      Conserved Domains (1) summary
      pfam00273
      Location:225 → 396
      Serum_albumin; Serum albumin family

    6. XM_039092168.2 → XP_038948096.1  alpha-fetoprotein related protein isoform X6

      Conserved Domains (2) summary
      pfam00273
      Location:30 → 205
      Serum_albumin; Serum albumin family
      cl00031
      Location:225 → 284
      ALBUMIN; Albumin domain, contains five or six internal disulphide bonds; albuminoid superfamily includes alpha-fetoprotein which binds various cations, fatty acids and bilirubin; vitamin D-binding protein which binds to vitamin D, its metabolites, and fatty acids; ...
    Nucleotide Protein Strain
    Heading Accession and Version

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