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    Golm2 golgi membrane protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362204, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Golm2provided by RGD
    Official Full Name
    golgi membrane protein 2provided by RGD
    Primary source
    RGD:1305985
    See related
    EnsemblRapid:ENSRNOG00000016357 AllianceGenome:RGD:1305985
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Casc4; RGD1305985
    Summary
    Predicted to be located in Golgi apparatus. Orthologous to human GOLM2 (golgi membrane protein 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 212.4), Lung (RPKM 81.1) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Golm2 in Genome Data Viewer
    Location:
    3q35
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (129280623..129349895)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (108827017..108896207)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (113818649..113887550)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene FERM domain containing 5 Neighboring gene barrier-to-autointegration factor-like Neighboring gene ribosomal protein S4, X-linked, pseudogene 2 Neighboring gene prohibitin 2, pseudogene 2 Neighboring gene uncharacterized LOC134486142 Neighboring gene CTD small phosphatase like 2 Neighboring gene eukaryotic translation initiation factor 3, subunit J Neighboring gene SPG11 vesicle trafficking associated, spatacsin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein GOLM2
    Names
    cancer susceptibility 4
    cancer susceptibility candidate 4
    gene associated with HER-2/neu overexpression
    protein CASC4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271283.2 → NP_001258212.1  protein GOLM2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8I6AP68, D3ZW58
      Related
      ENSRNOP00000044061.6, ENSRNOT00000044158.8
      Conserved Domains (1) summary
      TIGR02168
      Location:42 → 195
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      129280623..129349895
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039105461.2 → XP_038961389.1  protein GOLM2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AAC2, A0A8I6AP68
      Related
      ENSRNOP00000088652.1, ENSRNOT00000102816.2
      Conserved Domains (1) summary
      TIGR02168
      Location:42 → 195
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    Nucleotide Protein Strain
    Heading Accession and Version

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