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    Cenatac centrosomal AT-AC splicing factor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 689046, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cenatacprovided by RGD
    Official Full Name
    centrosomal AT-AC splicing factorprovided by RGD
    Primary source
    RGD:1597440
    See related
    EnsemblRapid:ENSRNOG00000012137 AllianceGenome:RGD:1597440
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ccdc84
    Summary
    Predicted to be involved in several processes, including chromosome separation; mRNA splicing, via spliceosome; and negative regulation of centrosome duplication. Predicted to be located in centrosome. Human ortholog(s) of this gene implicated in mosaic variegated aneuploidy syndrome 4. Orthologous to human CENATAC (centrosomal AT-AC splicing factor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 109.6), Lung (RPKM 94.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cenatac in Genome Data Viewer
    Location:
    8q22
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (53632777..53639661, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (44735968..44742859, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (48729695..48736574, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 37 member 4 Neighboring gene trafficking protein particle complex subunit 4 Neighboring gene ribosomal protein s25 Neighboring gene methyltransferase like 9, pseudogene 1 Neighboring gene forkhead box R1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in chromosome separation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of centrosome duplication ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    centrosomal AT-AC splicing factor
    Names
    coiled-coil domain containing 84
    coiled-coil domain-containing protein 84
    rCG58288-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398796.1 → NP_001385725.1  centrosomal AT-AC splicing factor

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6J3Z2, D4A553
      Related
      ENSRNOP00000103029.1, ENSRNOT00000152720.1
      Conserved Domains (1) summary
      pfam14968
      Location:7 → 322
      CCDC84; Coiled coil protein 84

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      53632777..53639661 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039082333.2 → XP_038938261.1  centrosomal AT-AC splicing factor isoform X2

      UniProtKB/TrEMBL
      A6J3Z2
      Conserved Domains (1) summary
      pfam14968
      Location:7 → 325
      CCDC84; Coiled coil protein 84

    2. XM_008766178.4 → XP_008764400.1  centrosomal AT-AC splicing factor isoform X1

      See identical proteins and their annotated locations for XP_008764400.1

      UniProtKB/TrEMBL
      A6J3Z2
      Related
      ENSRNOP00000016228.6, ENSRNOT00000016227.8
      Conserved Domains (1) summary
      pfam14968
      Location:7 → 329
      CCDC84; Coiled coil protein 84

    3. XM_063266159.1 → XP_063122229.1  centrosomal AT-AC splicing factor isoform X4

    4. XM_039082337.2 → XP_038938265.1  centrosomal AT-AC splicing factor isoform X3

      Conserved Domains (1) summary
      pfam14968
      Location:7 → 171
      CCDC84; Coiled coil protein 84

    RNA

    1. XR_010054025.1 RNA Sequence

    2. XR_005488134.2 RNA Sequence

    3. XR_010054027.1 RNA Sequence

    4. XR_005488135.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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