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    CG13126 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34323, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG13126provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032168
    Locus tag
    Dmel_CG13126
    See related
    AllianceGenome:FB:FBgn0032168
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.208; Dmel\CG13126; METTL17
    Summary
    Predicted to enable 4 iron, 4 sulfur cluster binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial small ribosomal subunit assembly. Predicted to be part of mitochondrial small ribosomal subunit. Is expressed in several structures, including anterior endoderm; dorsal pharyngeal muscle primordium; embryonic/larval midgut; embryonic/larval midgut primordium; and larval muscle cell. Orthologous to human METTL17 (methyltransferase like 17). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13126 in Genome Data Viewer
    Location:
    30F2-30F2; 2-38 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (9952072..9954181, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (9952072..9954181, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45949 Neighboring gene mir-87 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44872 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A cytological F1 RNAi screen for defects in Drosophila melanogaster female meiosis. Gilliland WD, et al. Genetics, 2024 May 7. PMID 38531678,
    2. The 18S ribosomal RNA m(6) A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. Leismann J, et al. EMBO Rep, 2020 Jul 3. PMID 32350990, Free PMC Article
    3. Age-specific variation in immune response in Drosophila melanogaster has a genetic basis. Felix TM, et al. Genetics, 2012 Jul. PMID 22554890, Free PMC Article
    4. Automated identification of putative methyltransferases from genomic open reading frames. Katz JE, et al. Mol Cell Proteomics, 2003 Aug. PMID 12872006
    5. A large-scale RNAi screen reveals that mitochondrial function is important for meiotic chromosome organization in oocytes. Nieken KJ, et al. Chromosoma, 2023 Mar. PMID 36648541, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial small ribosomal subunit assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13126-PA
    CG13126-PB
    NP_001285787.1
    NP_609330.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      9952072..9954181 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298858.1 → NP_001285787.1  uncharacterized protein Dmel_CG13126, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285787.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VL60
      Conserved Domains (1) summary
      pfam09243
      Location:156 → 441
      Rsm22; Mitochondrial small ribosomal subunit Rsm22

    2. NM_135486.5 → NP_609330.1  uncharacterized protein Dmel_CG13126, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609330.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VL60
      Related
      FBpp0079488
      Conserved Domains (1) summary
      pfam09243
      Location:156 → 441
      Rsm22; Mitochondrial small ribosomal subunit Rsm22
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VL60 Q9VL60

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