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    CG5339 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37794, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5339provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034925
    Locus tag
    Dmel_CG5339
    See related
    AllianceGenome:FB:FBgn0034925
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5339; drev; METTL9
    Summary
    Predicted to enable protein-L-histidine N-pros-methyltransferase activity. Is expressed in adult head and organism. Orthologous to human METTL9 (methyltransferase 9, His-X-His N1(pi)-histidine). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5339 in Genome Data Viewer
    Location:
    60A9-60A9; 2-105 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23896896..23898246, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19784419..19785769, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Decapping protein 1 Neighboring gene DNA ligase 1 Neighboring gene Upf3 Neighboring gene uncharacterized protein Neighboring gene Lost PHDs of trr Neighboring gene uncharacterized protein Neighboring gene Nucleosome assembly protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Histone recognition and nuclear receptor co-activator functions of Drosophila cara mitad, a homolog of the N-terminal portion of mammalian MLL2 and MLL3. Chauhan C, et al. Development, 2012 Jun. PMID 22569554, Free PMC Article
    2. The 18S ribosomal RNA m(6) A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. Leismann J, et al. EMBO Rep, 2020 Jul 3. PMID 32350990, Free PMC Article
    3. Wun2-mediated integrin recycling promotes apoptotic cell clearance in Drosophila melanogaster. Gao N, et al. Cell Death Differ, 2022 Dec. PMID 35840760, Free PMC Article
    4. Automated identification of putative methyltransferases from genomic open reading frames. Katz JE, et al. Mol Cell Proteomics, 2003 Aug. PMID 12872006
    5. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables protein-L-histidine N-pros-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5339-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23896896..23898246 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138002.4 → NP_611846.1  uncharacterized protein Dmel_CG5339 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611846.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W1H1
      Related
      FBpp0072129
      Conserved Domains (1) summary
      cl17173
      Location:32 → 302
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W1H1 Q9W1H1

    Gene LinkOut

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