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    hng3 hinge3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38090, updated on 9-Dec-2024

    Summary

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    Official Symbol
    hng3provided by FlyBase
    Official Full Name
    hinge3provided by FlyBase
    Primary source
    FLYBASE:FBgn0035160
    Locus tag
    Dmel_CG13897
    See related
    AllianceGenome:FB:FBgn0035160
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.557; CG13897; CG13987; Dmel\CG13897
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including embryonic/larval garland cell; embryonic/larval proventriculus; gland; imaginal disc; and larval central nervous system. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See hng3 in Genome Data Viewer
    Location:
    61C9-61C9; 3-0.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (737680..755489, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (737680..755489, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45411 Neighboring gene long non-coding RNA:CR43785 Neighboring gene transfer RNA:initiator Methionine-CAT 1-3 Neighboring gene extra macrochaetae Neighboring gene transfer RNA:Isoleucine-TAT 1-1 Neighboring gene transfer RNA:Isoleucine-TAT 1-2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of an arylalkylamine N-acyltransferase from Drosophila melanogaster that catalyzes the formation of long-chain N-acylserotonins. Dempsey DR, et al. FEBS Lett, 2014 Feb 14. PMID 24444601, Free PMC Article
    2. Stonewall and Brickwall: Two Partially Redundant Determinants Required for the Maintenance of Female Germline in Drosophila. Shukla V, et al. G3 (Bethesda), 2018 May 31. PMID 29669801, Free PMC Article
    3. The MADF-BESS domain factor Dip3 potentiates synergistic activation by Dorsal and Twist. Bhaskar V, et al. Gene, 2002 Oct 16. PMID 12459265
    4. Drosophila melanogaster heterochromatin protein HP1b plays important roles in transcriptional activation and development. Zhang D, et al. Chromosoma, 2011 Feb. PMID 20857302
    5. Gene duplication, lineage-specific expansion, and subfunctionalization in the MADF-BESS family patterns the Drosophila wing hinge. Shukla V, et al. Genetics, 2014 Feb. PMID 24336749, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    hinge3
    Names
    CG13897-PA
    CG13897-PB
    Hinge3
    hng3-PA
    hng3-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      737680..755489 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274293.1 → NP_001261222.1  hinge3, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261222.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PBH2, Q8SYS1
      Conserved Domains (2) summary
      smart00595
      Location:14 → 60
      MADF; subfamily of SANT domain
      pfam02944
      Location:209 → 243
      BESS; BESS motif

    2. NM_138213.3 → NP_612057.1  hinge3, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_612057.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W0N1
      Related
      FBpp0072497
      Conserved Domains (2) summary
      smart00595
      Location:5 → 91
      MADF; subfamily of SANT domain
      pfam02944
      Location:240 → 274
      BESS; BESS motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PBH2 M9PBH2
    Q8SYS1 Q8SYS1
    Q9W0N1 Q9W0N1

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