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    LOC8028743 E3 ubiquitin-protein ligase RNF123 [ Ixodes scapularis (black-legged tick) ]

    Gene ID: 8028743, updated on 31-Jul-2024

    Summary

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    Gene symbol
    LOC8028743
    Gene description
    E3 ubiquitin-protein ligase RNF123
    See related
    VectorBase:ISCP_038264; EnsemblRapid:LOC8028743
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Ixodes scapularis
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes
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    Genomic context

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    See LOC8028743 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    103 current ASM1692078v2 (GCF_016920785.2) Unplaced Scaffold NW_024609883.1 (101425351..101464834, complement)
    102 previous assembly Ixodes_scapularus_ComboLowHiFi (GCF_016920785.1) Unplaced Scaffold NW_024389570.1 (559555..599402)

    NW_024609883.1Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 29 Neighboring gene NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit NP15.6 Neighboring gene proton myo-inositol cotransporter Neighboring gene endochitinase A-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptome of the female synganglion of the black-legged tick Ixodes scapularis (Acari: Ixodidae) with comparison between Illumina and 454 systems. Egekwu N, et al. PLoS One, 2014. PMID 25075967, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis involved in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF123

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Ixodes scapularis Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1692078v2

    Genomic

    1. NW_024609883.1 Reference ASM1692078v2

      Range
      101425351..101464834 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040206757.3 → XP_040062691.1  E3 ubiquitin-protein ligase RNF123 isoform X1

      UniProtKB/TrEMBL
      A0A4D5S2S5
      Related
      XP_040062691.1, XM_040206757.3
      Conserved Domains (2) summary
      cd12882
      Location:102 → 229
      SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
      cd16541
      Location:1122 → 1162
      RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

    2. XM_029967000.4 → XP_029822860.2  E3 ubiquitin-protein ligase RNF123 isoform X2

      UniProtKB/TrEMBL
      A0A4D5S2S5
      Related
      XP_029822860.2, XM_029967000.4
      Conserved Domains (2) summary
      cd12882
      Location:102 → 229
      SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
      cd16541
      Location:1105 → 1145
      RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins

    3. XM_029966999.3 → XP_029822859.2  E3 ubiquitin-protein ligase RNF123 isoform X1

      UniProtKB/TrEMBL
      A0A4D5S2S5
      Related
      XP_029822859.2, XM_029966999.3
      Conserved Domains (2) summary
      cd12882
      Location:102 → 229
      SPRY_RNF123; SPRY domain at N-terminus of ring finger protein 123
      cd16541
      Location:1122 → 1162
      RING-HC_RNF123; RING finger, HC subclass, found in RING finger protein 123 (RNF123) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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