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    Pdk1 Phosphoinositide-dependent kinase 1 [ Anopheles arabiensis ]

    Gene ID: 120897320, updated on 23-May-2024

    Summary

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    Gene symbol
    Pdk1
    Gene description
    Phosphoinositide-dependent kinase 1
    See related
    VectorBase:AARA21_003061
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Anopheles arabiensis
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; Anophelinae; Anopheles
    Orthologs
    fruit fly all
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    Genomic context

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    See Pdk1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    100 current AaraD3 (GCF_016920715.1) 2 NC_053517.1 (5247038..5250373, complement)

    Chromosome 2 - NC_053517.1Genomic Context describing neighboring genes Neighboring gene PTPRF interacting protein alpha Neighboring gene toll-like receptor 3 Neighboring gene Myocardin-related transcription factor Neighboring gene acyl-CoA synthetase short-chain family member 3, mitochondrial Neighboring gene neuropeptide receptor myosuppressin

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_053517.1 Chromosome 2 Reference AaraD3 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    3-phosphoinositide-dependent protein kinase 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Anopheles arabiensis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference AaraD3 Primary Assembly

    Genomic

    1. NC_053517.1 Reference AaraD3 Primary Assembly

      Range
      5247038..5250373 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040302130.1 → XP_040158064.1  3-phosphoinositide-dependent protein kinase 1 isoform X2

      Conserved Domains (2) summary
      cd01262
      Location:489 → 588
      PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
      cd05581
      Location:18 → 336
      STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1

    2. XM_040302121.1 → XP_040158055.1  3-phosphoinositide-dependent protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A2C9GQJ8
      Conserved Domains (2) summary
      cd01262
      Location:513 → 612
      PH_PDK1; 3-Phosphoinositide dependent protein kinase 1 (PDK1) pleckstrin homology (PH) domain
      cd05581
      Location:42 → 360
      STKc_PDK1; Catalytic domain of the Serine/Threonine Kinase, Phosphoinositide-dependent kinase 1
    Nucleotide Protein
    Heading Accession and Version

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