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    GRB14 growth factor receptor bound protein 14 [ Puma yagouaroundi (jaguarundi) ]

    Gene ID: 121030630, updated on 22-Mar-2024

    Summary

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    Gene symbol
    GRB14
    Gene description
    growth factor receptor bound protein 14
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Puma yagouaroundi
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Puma
    Orthologs
    human mouse all
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    Genomic context

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    See GRB14 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    100 current PumYag (GCF_014898765.1) Unplaced Scaffold NW_024412395.1 (46020762..46140462, complement)

    NW_024412395.1Genomic Context describing neighboring genes Neighboring gene tigger transposable element-derived protein 1-like Neighboring gene small nucleolar RNA SNORA25 Neighboring gene uncharacterized LOC121030633 Neighboring gene cordon-bleu WH2 repeat protein like 1 Neighboring gene complement component 1 Q subcomponent-binding protein, mitochondrial-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_024412395 Unplaced Scaffold Reference PumYag Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in insulin receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of insulin receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    growth factor receptor-bound protein 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Puma yagouaroundi Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference PumYag Primary Assembly

    Genomic

    1. NW_024412395.1 Reference PumYag Primary Assembly

      Range
      46020762..46140462 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040475214.1 → XP_040331148.1  growth factor receptor-bound protein 14 isoform X1

      Conserved Domains (4) summary
      cd10414
      Location:452 → 559
      SH2_Grb14; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 14 (Grb14) proteins
      cd01259
      Location:230 → 370
      PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
      cd16139
      Location:107 → 191
      RA_GRB14; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 14
      pfam08947
      Location:389 → 433
      BPS; BPS (Between PH and SH2)

    2. XM_040475216.1 → XP_040331150.1  growth factor receptor-bound protein 14 isoform X3

      Conserved Domains (4) summary
      cd10414
      Location:401 → 508
      SH2_Grb14; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 14 (Grb14) proteins
      cd01259
      Location:230 → 319
      PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
      cd16139
      Location:107 → 191
      RA_GRB14; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 14
      pfam08947
      Location:338 → 382
      BPS; BPS (Between PH and SH2)

    3. XM_040475215.1 → XP_040331149.1  growth factor receptor-bound protein 14 isoform X2

      Conserved Domains (4) summary
      cd10414
      Location:433 → 540
      SH2_Grb14; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 14 (Grb14) proteins
      cd01259
      Location:230 → 351
      PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
      cd16139
      Location:107 → 191
      RA_GRB14; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 14
      pfam08947
      Location:370 → 414
      BPS; BPS (Between PH and SH2)

    4. XM_040475217.1 → XP_040331151.1  growth factor receptor-bound protein 14 isoform X4

      Conserved Domains (3) summary
      cd10414
      Location:365 → 472
      SH2_Grb14; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 14 (Grb14) proteins
      cd01259
      Location:143 → 283
      PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
      cd16139
      Location:20 → 104
      RA_GRB14; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 14

    5. XM_040475218.1 → XP_040331152.1  growth factor receptor-bound protein 14 isoform X5

      Conserved Domains (4) summary
      cd10414
      Location:346 → 453
      SH2_Grb14; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 14 (Grb14) proteins
      cd01259
      Location:143 → 264
      PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
      cd16139
      Location:20 → 104
      RA_GRB14; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 14
      pfam08947
      Location:283 → 327
      BPS; BPS (Between PH and SH2)
    Nucleotide Protein
    Heading Accession and Version

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