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    NEURL1 neuralized E3 ubiquitin protein ligase 1 [ Gallus gallus (chicken) ]

    Gene ID: 423875, updated on 3-Dec-2024

    Summary

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    Symbol
    NEURL1provided by CGNC
    Full Name
    neuralized E3 ubiquitin protein ligase 1provided by CGNC
    Primary source
    CGNC:6274
    See related
    Ensembl:ENSGALG00010021166
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    NEURL
    Orthologs
    human mouse all
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    Genomic context

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    See NEURL1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (24452141..24586529)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (24343481..24478905)

    Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene calcium homeostasis modulator 2 Neighboring gene calcium homeostasis modulator 1 Neighboring gene calcium homeostasis modulator 3 Neighboring gene SH3 and PX domains 2A Neighboring gene uncharacterized LOC121111060 Neighboring gene STN1, CST complex subunit Neighboring gene STE20 like kinase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase NEURL1
    Names
    neuralized homolog
    neuralized-like protein 1A
    NP_001012928.2
    XP_015144133.1
    XP_040558370.1
    XP_040558371.1
    XP_040558373.1
    XP_046776276.1
    XP_046776277.1
    XP_046776278.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012910.3 → NP_001012928.2  E3 ubiquitin-protein ligase NEURL1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000232
      UniProtKB/TrEMBL
      F1P1U7, Q5ZLA1
      Related
      ENSGALP00010030470.1, ENSGALT00010051279.1
      Conserved Domains (3) summary
      smart00588
      Location:44 → 166
      NEUZ; domain in neuralized proteins
      cd16785
      Location:500 → 543
      mRING-HC-C3HC5_NEU1A; Modified RING finger, HC subclass (C3HC5-type), found in neuralized-like protein 1A (NEURL1A) and similar proteins
      pfam07177
      Location:277 → 427
      Neuralized

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      24452141..24586529
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040702436.2 → XP_040558370.1  E3 ubiquitin-protein ligase NEURL1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0ZI69
      Conserved Domains (3) summary
      smart00588
      Location:61 → 183
      NEUZ; domain in neuralized proteins
      cd16785
      Location:557 → 600
      mRING-HC-C3HC5_NEU1A; Modified RING finger, HC subclass (C3HC5-type), found in neuralized-like protein 1A (NEURL1A) and similar proteins
      cl26914
      Location:291 → 411
      Neuralized

    2. XM_015288647.4 → XP_015144133.1  E3 ubiquitin-protein ligase NEURL1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZI69, A0A8V0ZI78
      Related
      ENSGALP00010030495.1, ENSGALT00010051304.1
      Conserved Domains (4) summary
      smart00588
      Location:61 → 183
      NEUZ; domain in neuralized proteins
      pfam07177
      Location:294 → 359
      Neuralized; Neuralized
      pfam13920
      Location:517 → 565
      zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
      cl02614
      Location:293 → 443
      SPRY; SPRY domain

    3. XM_040702439.1 → XP_040558373.1  E3 ubiquitin-protein ligase NEURL1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZI69
      Conserved Domains (2) summary
      cd16785
      Location:482 → 525
      mRING-HC-C3HC5_NEU1A; Modified RING finger, HC subclass (C3HC5-type), found in neuralized-like protein 1A (NEURL1A) and similar proteins
      cl26914
      Location:1 → 108
      Neuralized

    4. XM_040702437.2 → XP_040558371.1  E3 ubiquitin-protein ligase NEURL1 isoform X2

      UniProtKB/TrEMBL
      Q5ZLA1
      Conserved Domains (3) summary
      smart00588
      Location:44 → 166
      NEUZ; domain in neuralized proteins
      cd16785
      Location:540 → 583
      mRING-HC-C3HC5_NEU1A; Modified RING finger, HC subclass (C3HC5-type), found in neuralized-like protein 1A (NEURL1A) and similar proteins
      cl26914
      Location:274 → 394
      Neuralized

    RNA

    1. XR_005860626.2 RNA Sequence

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      24343481..24478905
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046920321.1 → XP_046776277.1  E3 ubiquitin-protein ligase NEURL1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZI69, A0A8V0ZI78

    2. XM_046920322.1 → XP_046776278.1  E3 ubiquitin-protein ligase NEURL1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZI69

    3. XM_046920320.1 → XP_046776276.1  E3 ubiquitin-protein ligase NEURL1 isoform X2

      UniProtKB/TrEMBL
      Q5ZLA1

    RNA

    1. XR_006935014.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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